Methamphetamine

MA

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	149.23 g/mol ^[1]
Predicted LogP	2.1 ^[1]

Structural Identifiers []
Molecular formula	C₁₀H₁₅N ^[1]
IUPAC name	N-methyl-1-phenylpropan-2-amine ^[1]
SMILES	CC(CC1=CC=CC=C1)NC ^[1]
InChI	InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3 ^[1]
InChIKey	MYWUZJCMWCOHBA-UHFFFAOYSA-N ^[1]

Pharmacokinetics[]
Elimination half-life	9 – 12 hours (range 5 – 30 hours); irrespective of route
Duration of action	8 – 12 hours^[4]

Methamphetamine (also known as methamphetamine, Methamphetamine, Pervertin, Anadrex, (2-Methylaminopropyl)benzene, 7632-10-2, Methamphetamine, DL-, N,α-Dimethylbenzeneethanamine, Benzeneethanamine, N,α-dimethyl- or 13ZT6YG5SD) is a stimulant substance of the amphetamine class.

Chemistry

Stereochemistry []

Methamphetamine is a racemic mixture of the enantiomers.

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

x86pup / Methamphetamine []
Routes: Oral

0xea / Methamphetamine []
Routes: Oral (10-50mg) Insufflated (10-20mg) Intrarectal (5-20mg) Subcutaneous (4.2-15mg) Intramuscular (10-15mg) Onset: 30-60 seconds Intravenous (10-60mg) Onset: 10-15 seconds Duration: 1-8 hours Vaporized Salts: Hydrochloride Source: Crystal Meth (Ephedrine): DNM Germany Crystal Meth: Goerlitzer park Indication: executive dysfunction Active Effects: strong stimulation short-acting intense cognitive euphoria intense focus enhancement up to 5+ days on end strong wakefulness up to 6+ days strong dry mouth and thirst suppression strong compulsive redosing increased libido Side Effects: headache psychosis time compression (perception of music and other human beings comically speed up) hallucination of a man sitting in a chair next to me taunting me; pieces of dust manifesting as hallucinations of spider like creatures lights shine through my courtains rain coming from the sealing auditory hallucinations of phantom music playing as if I were wearing headphones autonomous voice communication (voices of my mother and father screaming at each other for hours about my drug habit; mocking and laughter; police officer screaming in stair-way all night; police radio chatter blaring through the street spelling my name; hallucinations of my partner making fun of me to her friends and threatening to seriously hurt me) delusion (cotards syndrome)

0xea / Methamphetamine []

Routes:
- Oral (10-50mg)
- Insufflated (10-20mg)
- Intrarectal (5-20mg)
- Subcutaneous (4.2-15mg)
- Intramuscular (10-15mg)
  - Onset: 30-60 seconds
- Intravenous (10-60mg)
  - Onset: 10-15 seconds
  - Duration: 1-8 hours
- Vaporized
Salts:
- Hydrochloride
Source:
- Crystal Meth (Ephedrine): DNM Germany
- Crystal Meth: Goerlitzer park
Indication:
- executive dysfunction
Active Effects:
- strong stimulation
- short-acting intense cognitive euphoria
- intense focus enhancement up to 5+ days on end
- strong wakefulness up to 6+ days
- strong dry mouth and thirst suppression
- strong compulsive redosing
- increased libido
Side Effects:
- headache
- psychosis
- time compression (perception of music and other human beings comically speed up)
- hallucination of a man sitting in a chair next to me taunting me; pieces of dust manifesting as hallucinations of spider like creatures
- lights shine through my courtains
- rain coming from the sealing
- auditory hallucinations of phantom music playing as if I were wearing headphones
- autonomous voice communication (voices of my mother and father screaming at each other for hours about my drug habit; mocking and laughter; police officer screaming in stair-way all night; police radio chatter blaring through the street spelling my name; hallucinations of my partner making fun of me to her friends and threatening to seriously hurt me)
- delusion (cotards syndrome)

Legal status []

Australia: Methamphetamine is a S8 substance.
Brazil: Methamphetamine is a F2 substance.^[3]
Canada: Methamphetamine is a Schedule I substance.
Germany: Methamphetamine is a Anlage II substance.
New Zealand: Methamphetamine is a Class A substance.
United Kingdom: Methamphetamine is a Class A substance.
United States: Methamphetamine is a Schedule I under the "Controlled Substances Act (CSA)".
European Union: Methamphetamine is a prescription only substance.
United Nations: Methamphetamine is a Schedule II substance.

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 1206, methamphetamine. Accessed January 30, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/1206
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Methamphetamine. UNII: 13ZT6YG5SD. Global Substance Registration System. Accessed January 30, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/13ZT6YG5SD
Anvisa. RDC Nº 804 – Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed January 30, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451
Courtney KE, Ray LA. Methamphetamine: an update on epidemiology, pharmacology, clinical phenomenology, and treatment literature. Drug Alcohol Depend. October 1, 2014; 143():11–21.

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