Dextromethamphetamine

Dextromethamphetamine

Salts []
Dextromethamphetamine hydrochloride

Dextromethamphetamine saccharate

Dextromethamphetamine tartrate

Molecular structure via molpic based on CDK

Rotamer []

Conformer structure via 3Dmol.js

Physical properties []
Molecular mass	149.23 g/mol ^[1]
Appearance	Clear, colorless liquid ^[1]
Odor	Characteristic odor resembling geranium leaves ^[1]
Taste	Bitter-tasting ^[1]
Melting point	170-2 °C ^[1]
Boiling point	212 °C ^[1]
Decomposition	When heated to decomposition it emits toxic vapors of Nitric oxides. ^[1]
Solubility	In water, 0.5 g/mL ^[1]
Predicted LogP	2.1 ^[1]

Structural Identifiers []
Molecular formula	C₁₀H₁₅N ^[1]
IUPAC name	(2S)-N-methyl-1-phenylpropan-2-amine ^[1]
SMILES	C[C@@H](CC1=CC=CC=C1)NC ^[1]
InChI	InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1 ^[1]
InChIKey	MYWUZJCMWCOHBA-VIFPVBQESA-N ^[1]

Pharmacokinetics[]
Elimination half-life	9 – 12 hours (range 5 – 30 hours); irrespective of route
Duration of action	8 – 12 hours^[4]

Dosing[]

Insufflated []
Light	≤ 15 mg(34x - 41.5%)
Common	15 - 20 mg(13x - 15.9%)
Strong	20 - 27.3 mg(14x - 17.1%)
Heavy	27.3 - 31.8 mg(12x - 14.6%)
Extreme	31.8 mg +(9x - 11%)

Intravenous []
Light	≤ 56.2 mg(30x - 47.6%)
Common	56.2 - 130 mg(2x - 3.2%)
Strong	130 - 180 mg(22x - 34.9%)
Heavy	180 - 200 mg(6x - 9.5%)
Extreme	200 mg +(3x - 4.8%)

Oral []
Light	≤ 20 mg(5x - 83.3%)
Common	20 mg
Strong	20 mg
Heavy	20 - 22 mg
Extreme	22 mg +(1x - 16.7%)

Intrarectal []
Light	≤ 51.2 mg(4x - 57.1%)
Common	51.2 mg
Strong	40 - 200 mg(1x - 14.3%)
Heavy	200 - 300 mg(2x - 28.6%)
Extreme	300 mg +

Vaporized []
Light	≤ 11.1 mg(12x - 57.1%)
Common	11.1 mg
Strong	10 - 25 mg(4x - 19%)
Heavy	25 - 50 mg(4x - 19%)
Extreme	50 mg +(1x - 4.8%)

Statistically derived dosages via DBI-IGS

We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Dextromethamphetamine (also known as Methamphetamine, Metamfetamine, Deoxyephedrine, Metamphetamine, Desoxyephedrine, Methylamphetamine, N-Methylamphetamine, Norodin, Phenylisopropylmethylamine or (S)-Methamphetamine) is a stimulant substance of the amphetamine class.

Chemistry

Salts []

Dextromethamphetamine is typically found in the form of its hydrochloride, saccharate and tartrate salts.

Stereochemistry []

Dextromethamphetamine is a absolute mixture.

Pharmacology

ATC Classification

In the nervous system (N) dextromethamphetamine acts as a stimulant (N06B), sympathomimetic (N06BA), metamfetamine (N06BA03) and psychoanaleptic (N06).^[1]

Subjective effects []

class / Stimulant

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

0xea / Dextromethamphetamine []
Routes: Oral (10 - 50mg) Insufflated (10 - 20mg) Intrarectal (5 - 20mg) Subcutaneous (4.2 - 15mg) Intramuscular (10 - 15mg) Onset: 30 - 60 s Duration: ? Intravenous (15 - 45mg) Onset: 10 - 15 s Duration: 1 - 8 h Vaporized Salts: Hydrochloride Source: Crystal Meth (Ephedrine): DNM Germany Indication: motivation suppression (executive dysfunction) depression sleepiness cognitive dysphoria Active Effects: strong stimulation short-acting intense cognitive euphoria intense focus enhancement (often resulting in a state of day long hyper-focus which may or may not be counter-productive) strong wakefulness (up to 6+ days) strong motivation enhancement strong stamina enhancement strong dry mouth intense appetite suppression and thirst suppression strong compulsive redosing increased libido without tolerance strong depression reduction acute relief of constipation Side Effects: strong addiction (+10g consumed; compulsive drug seeking on the street; psychological breakdown; intense mental dulling and tolerance) headache psychosis shadow people time compression (perception of music and other human beings comically speed up) autonomous entity (hallucination of a man sitting in a chair next to me taunting me; pieces of dust manifesting as hallucinations of spider like creatures) lights shine through my courtains rain coming from the sealing auditory hallucination (phantom music playing as if I were wearing headphones) autonomous voice communication (voices of my mother and father screaming at each other for hours about my drug habit; mocking and laughter; police officer screaming in stair-way all night; police radio chatter blaring through the street spelling my name; hallucinations of my partner making fun of me to her friends and threatening to seriously hurt me) delusion (cotard's syndrome) After Effects: feelings of impending doom (for 1-5 days) panic attack (for 1-5 days) depression motivation suppression (for 1-2 weeks)

0xea / Dextromethamphetamine []

Routes:

Oral (10 - 50mg)
Insufflated (10 - 20mg)
Intrarectal (5 - 20mg)
Subcutaneous (4.2 - 15mg)
Intramuscular (10 - 15mg)
Onset: 30 - 60 s
Duration: ?
Intravenous (15 - 45mg)
Onset: 10 - 15 s
Duration: 1 - 8 h
Vaporized

Salts:

Hydrochloride

Source:

Crystal Meth (Ephedrine): DNM Germany

Indication:

motivation suppression (executive dysfunction)
depression
sleepiness
cognitive dysphoria

Active Effects:

strong stimulation
short-acting intense cognitive euphoria
intense focus enhancement (often resulting in a state of day long hyper-focus which may or may not be counter-productive)
strong wakefulness (up to 6+ days)
strong motivation enhancement
strong stamina enhancement
strong dry mouth
intense appetite suppression and thirst suppression
strong compulsive redosing
increased libido
without tolerance strong depression reduction
acute relief of constipation

Side Effects:

strong addiction (+10g consumed; compulsive drug seeking on the street; psychological breakdown; intense mental dulling and tolerance)
headache
psychosis
shadow people
time compression (perception of music and other human beings comically speed up)
autonomous entity (hallucination of a man sitting in a chair next to me taunting me; pieces of dust manifesting as hallucinations of spider like creatures)
lights shine through my courtains
rain coming from the sealing
auditory hallucination (phantom music playing as if I were wearing headphones)
autonomous voice communication (voices of my mother and father screaming at each other for hours about my drug habit; mocking and laughter; police officer screaming in stair-way all night; police radio chatter blaring through the street spelling my name; hallucinations of my partner making fun of me to her friends and threatening to seriously hurt me)
delusion (cotard's syndrome)

After Effects:

feelings of impending doom (for 1-5 days)
panic attack (for 1-5 days)
depression
motivation suppression (for 1-2 weeks)

Legal status []

Australia: Dextromethamphetamine is a S8 substance.
Brazil: Dextromethamphetamine is a F2 substance.^[3]
Canada: Dextromethamphetamine is a Schedule I substance.
Germany: Dextromethamphetamine is a Anlage II substance.
New Zealand: Dextromethamphetamine is a Class A substance.
United Kingdom: Dextromethamphetamine is a Class A substance.
United States: Dextromethamphetamine is a Schedule I under the "Controlled Substances Act (CSA)".
European Union: Dextromethamphetamine is a prescription only substance.
United Nations: Dextromethamphetamine is a Schedule II substance.

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 10836, Methamphetamine. Accessed April 29, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/10836
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Dextromethamphetamine. UNII: 44RAL3456C. Global Substance Registration System. Accessed April 29, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/44RAL3456C
Anvisa. RDC Nº 804 – Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed April 29, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451
Courtney KE, Ray LA. Methamphetamine: an update on epidemiology, pharmacology, clinical phenomenology, and treatment literature. Drug Alcohol Depend. October 1, 2014; 143():11–21.

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