Amphetamine
| Speed | |
|---|---|
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 135.21 g/mol [1] |
| Density | 0.913 at 77 °F (EPA, 1998) - Less dense than water; will float g/cm3 [1] |
| Appearance | Mobile liquid [1] |
| Odor | Amine odor [1] |
| Taste | Acrid, burning taste [1] |
| Melting point | 25 °C [1] |
| Boiling point | 392 to 397 °F at 760 mmHg (EPA, 1998) [1] |
| Decomposition | When heated to decomposition it emits toxic fumes of nitroxides. [1] |
| Solubility | Moderate solubility [1] |
| Predicted LogP | 1.8 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C9H13N [1] |
| IUPAC name | 1-phenylpropan-2-amine [1] |
| SMILES | CC(CC1=CC=CC=C1)N [1] |
| InChI | InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3 [1] |
| InChIKey | KWTSXDURSIMDCE-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Duration of action | Immediate release dosing: 3 – 6 hours Extended release dosing: 8 – 12 hours |
| Dosing[] |
|---|
| Insufflated [] | |
|---|---|
| Light | ≤ 13.2 mg(518x - 25.4%) |
| Common | 13.2 - 20 mg(635x - 31.2%) |
| Strong | 20 - 30 mg(449x - 22%) |
| Heavy | 30 - 44 mg(233x - 11.4%) |
| Extreme | 44 mg +(202x - 9.9%) |
| Intravenous [] | |
|---|---|
| Light | ≤ 25 mg(430x - 46.7%) |
| Common | 25 - 30 mg(178x - 19.3%) |
| Strong | 30 - 35 mg(165x - 17.9%) |
| Heavy | 35 - 40 mg(75x - 8.1%) |
| Extreme | 40 mg +(73x - 7.9%) |
| Sublingual [] | |
|---|---|
| Light | ≤ 13.9 mg(2x - 40%) |
| Common | 13.9 - 15 mg(1x - 20%) |
| Strong | 15 - 37.5 mg(1x - 20%) |
| Heavy | 37.5 - 45 mg |
| Extreme | 45 mg +(1x - 20%) |
| Oral [] | |
|---|---|
| Light | ≤ 17 mg(374x - 25.9%) |
| Common | 17 - 30 mg(446x - 30.8%) |
| Strong | 30 - 50 mg(305x - 21.1%) |
| Heavy | 50 - 97 mg(178x - 12.3%) |
| Extreme | 97 mg +(143x - 9.9%) |
| Intrarectal [] | |
|---|---|
| Light | ≤ 40.7 mg(19x - 33.9%) |
| Common | 40.7 - 70 mg(11x - 19.6%) |
| Strong | 70 - 100 mg(15x - 26.8%) |
| Heavy | 100 - 162.5 mg(5x - 8.9%) |
| Extreme | 162.5 mg +(6x - 10.7%) |
Statistically derived dosages via DBI-IGS We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly. |
Amphetamine (also known as Amfetamine, 1-Phenyl-2-aminopropane, Desoxynorephedrine, Norephedrane, Elastonon, Fenopromin, Phenedrine, β-Aminopropylbenzene, Propisamine or Psychedrine) is a stimulant substance of the amphetamine class.
Chemistry
Stereochemistry []
Amphetamine is a racemic mixture of the enantiomers.
| Stereoisomerism |
|---|
| Stereoisomer enumberation with rdkit |
Druglikeness
Lipinski's rule of five
Amphetamine matches Lipinski's rule of five.Pharmacology
ATC Classification
In the nervous system (N) amphetamine acts as a stimulant (N06B), sympathomimetic (N06BA) and psychoanaleptic (N06).[1]Subjective effects []
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Legal status []
- Australia: Amphetamine is a Schedule 8 substance.
- Brazil: Amphetamine is a A3 substance.
- Canada: Amphetamine is a Schedule I substance.
- Germany: Amphetamine is a Anlage III substance.
- New Zealand: Amphetamine is a Class B substance.
- United Kingdom: Amphetamine is a Class B substance.
- United States: Amphetamine is a List of Schedule II controlled substances (U.S.)|Schedule II substance.[2]
- United Nations: Amphetamine is a Schedule II substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3007, Amphetamine. Accessed June 17, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/3007
Ingersoll J. Amphetamine, Methamphetamine, and Optical Isomers. Bureau of Narcotics and Dangerous Drugs}. July 7, 1971. Accessed June 17, 2026. https://archives.federalregister.gov/issue_slice/1971/7/7/12730-12734.pdf
Adderall- dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablet. Teva Pharmaceuticals USA, Inc.. November 8, 2019. Accessed June 17, 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f22635fe-821d-4cde-aa12-419f8b53db81