Amphetamine | |
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Salts [] | |
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Amphetamine chlorphenoxyacetate | |
Amphetamine hemisulfate | |
Amphetamine hydrochloride | |
Amphetamine hemiaspartate | |
Amphetamine adipate | |
Amphetamine tartrate | |
Amphetamine phosphate | |
(+)-Amphetamine hemisaccharate | |
(-)-Amphetamine succinate | |
Molecular structure via molpic based on CDK |
Rotamer [] | |
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Physical properties [] | |
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Molecular mass | 135.21 g/mol [1] |
Density | 0.913 at 77 °F (EPA, 1998) - Less dense than water; will float g/cm3 [1] |
Appearance | Mobile liquid [1] |
Odor | Amine odor [1] |
Taste | Acrid, burning taste [1] |
Melting point | 25 °C [1] |
Boiling point | 392 to 397 °F at 760 mmHg (EPA, 1998) [1] |
Decomposition | When heated to decomposition it emits toxic fumes of nitroxides. [1] |
Solubility | Moderate solubility [1] |
Predicted LogP | 1.8 [1] |
Structural Identifiers [] | |
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Molecular formula | C9H13N [1] |
IUPAC name | 1-phenylpropan-2-amine [1] |
SMILES | CC(CC1=CC=CC=C1)N [1] |
InChI | InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3 [1] |
InChIKey | KWTSXDURSIMDCE-UHFFFAOYSA-N [1] |
Toxicity [] | |
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LDLo | Rat: - intraperitoneal: 23 mg/kg - intravenous: 20 mg/kg Dog: - subcutaneous: 20 mg/kg Monkey: - subcutaneous: 20 mg/kg Rabbit: - subcutaneous: 20 mg/kg - intravenous: 25 mg/kg Guinea pig: - oral: 200 mg/kg - subcutaneous: 20 mg/kg - parenteral: 20 mg/kg |
LD50 | Rat: - oral: 30 mg/kg - subcutaneous: 180 mg/kg Mouse: - oral: 21 mg/kg - intraperitoneal: 5500 μg/kg - subcutaneous: 15 mg/kg - intravenous: 15 mg/kg Mammal (species unspecified): - oral: 135 mg/kg - intraperitoneal: 65 mg/kg |
Amphetamine
Amphetamine (also known as Amphetamine, Amfetamine, Desoxynorephedrine, Norephedrane, 1-Phenyl-2-aminopropane, Elastonon, Fenopromin, Phenedrine, β-Aminopropylbenzene or Propisamine) is a stimulant substance of the amphetamine class.
Chemistry
Salts []
Amphetamine is typically found in the form of its chlorphenoxyacetate, hemisulfate, hydrochloride, hemiaspartate, adipate, tartrate, phosphate, hemisaccharate and succinate salts.
Stereochemistry []
Amphetamine is a racemic mixture of the enantiomers
Stereoisomers |
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Subjective effects
Anodyne Usernotes [] | |
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magnus / Amphetamine[sulfate] via Oral and Insufflation | focus enhancement; music enhancement; wakefulness; insomnia; pupil dilation; little euphoria, suppression of hunger and thirst |
0xea / Amphetamine[freebase][sulfate][hydrochloride] via Oral, Insufflated, Intrarectal, Subcutaneous, Intramuscular, Intravenous, Inhaled, Vaporized and Sublingual | Moderate Stimulation; Moderate Euphoria; Strong Vasoconstriction; Practical via Intravenous Injection, 1 minute comeup 3-4 hour duration; Practical via Subcutaneous Injection 25 minute comeup |
See also []
External links []
- Amphetamine / Dextroamphetamine (Wikipedia)
- Amphetamine / Dextroamphetamine / Dextroamphetamine (Wikidata)
- Amphetamine / Dextroamphetamine (DrugBank)
- Amphetamine / Dextroamphetamine / Dextroamphetamine (PubChem)
- Amphetamine / Dextroamphetamine / Dextroamphetamine (ChEMBL)
- Amphetamine / Dextroamphetamine / Dextroamphetamine (ChEBI)
- Amphetamine / Dextroamphetamine / Dextroamphetamine (Common Chemistry)
- Amphetamine / Dextroamphetamine / Dextroamphetamine (HMDB)
- Amphetamine / Dextroamphetamine (KEGG)
- Amphetamine / Dextroamphetamine / Dextroamphetamine (UNII)
- Amphetamine / Dextroamphetamine / Dextroamphetamine (EPA DSSTox)
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3007, Amphetamine. Accessed August 20, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/3007
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Amphetamine. UNII: CK833KGX7E. Global Substance Registration System. Accessed August 20, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/CK833KGX7E