AnodyneWiki

Diazepam

Valium
Diazepam
Salts
[]
Diazepam hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
284.74 g/mol [1]
AppearanceColorless to light yellow crysytals [1]
OdorPractically no odor [1]
Melting point257 to 259 °F (NTP, 1992) [1]
DecompositionWhen heated to decomp it emits very toxic fumes of hydrogen chloride and NO(x) [1]
Solubilityless than 1 mg/mL at 68 °F (NTP, 1992) [1]
[1]
Structural Identifiers
[]
C16H13ClN2[1]
7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one [1]
CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3 [1]
InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 [1]
InChIKeyAAOVKJBEBIDNHE-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-life(50 hours); 20 – 100 hours (32 – 200 hours for main active metabolite desmethyldiazepam)[5]
Dosing[]
Oral
[]
Light≤ 9.5 mg(30x - 25.6%)
Common9.5 - 10 mg(37x - 31.6%)
Strong10 - 20 mg(37x - 31.6%)
Heavy20 - 29.2 mg
Extreme29.2 mg +(13x - 11.1%)
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Diazepam (also known as Diazepam, Valium, Ansiolisina, Diazemuls, Apaurin, Faustan, Relanium, Seduxen, Sibazon or Stesolid) is a substance of the benzodiazepine class.

Chemistry

Salts []

Diazepam is typically found in the form of its hydrochloride salt.

 []

Diazepam is a achiral mixture.

Pharmacology

In the () diazepam acts as a anxiolytic (), benzodiazepine derivative (), diazepam () and psycholeptic ().[1]

Interactions []

induction / inhibition
induction / inhibition

Subjective effects []

alina / Diazepam []
Routes:
  • Oral (10.0mg)
bonzi / Diazepam []
Routes:
  • Oral (2.5 - 25mg)
magnus / Diazepam []
Routes:
  • Oral
0xea / Diazepam []
Routes:
  • Oral (5 - 30mg)
  • Intravenous (5 - 10mg)
Indication:Active Effects:Notes:

Experience reports []

 []

  • Australia: Diazepam is a S4 substance.[3]
  • Brazil: Diazepam is a B1 substance.
  • Canada: Diazepam is a Schedule IV substance.
  • Germany: Diazepam is a prescription only/Anlage III substance.
  • New Zealand: Diazepam is a Class C5 substance.
  • United Kingdom: Diazepam is a Class C substance.[4]
  • United States: Diazepam is a Schedule I under the "Controlled Substances Act (CSA)".
  • European Union: Diazepam is a prescription only substance.
  • United Nations: Diazepam is a schedule IV substance.

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 3016, Diazepam. Accessed May 3, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/3016

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Diazepam. UNII: Q3JTX2Q7TU. Global Substance Registration System. Accessed May 3, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/Q3JTX2Q7TU

  3. Valium. January 31, 2020. Accessed May 3, 2026. https://www.nps.org.au/medicine-finder/valium-tablets#full-pi

  4. Misuse of Drugs Act 1971}. Accessed May 3, 2026. https://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/III/paragraph/1

  5. Diazepam Tablets BP 10 mgs – Summary of Product Characteristics (SmPC). September 16, 2019. Accessed May 3, 2026. https://www.medicines.org.uk/emc/product/4522/smpc