Dextroamphetamine

Dextroamphetamine

Salts []
Dextroamphetamine hemisaccharate

Dextroamphetamine phosphate

Dextroamphetamine hemisulfate

Dextroamphetamine adipate

Dextroamphetamine hydrochloride

Molecular structure via molpic based on CDK

Rotamer []

Conformer structure via 3Dmol.js

Physical properties []
Molecular mass	135.21 g/mol ^[1]
Density	0.949 g/cu cm at 15 °C g/cm³ ^[1]
Appearance	Colorless liquid ^[1]
Melting point	27.5 °C ^[1]
Boiling point	203.5 °C ^[1]
Decomposition	When heated to decomposition it emits toxic nitroxides. ^[1]
Solubility	Moderately Soluble ^[1]
Predicted LogP	1.8 ^[1]

Structural Identifiers []
Molecular formula	C₉H₁₃N ^[1]
IUPAC name	(2S)-1-phenylpropan-2-amine ^[1]
SMILES	C[C@@H](CC1=CC=CC=C1)N ^[1]
InChI	InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1 ^[1]
InChIKey	KWTSXDURSIMDCE-QMMMGPOBSA-N ^[1]

Pharmacokinetics[]
Elimination half-life	9 – 11 hours^[5]pH-dependent: 7 – 34 hours
Duration of action	Immediate release dosing: 3 – 6 hours^[6]Extended release dosing: 8 – 12 hours^[7]

Dosing[]

Insufflated []
Light	≤ 7.1 mg(2x - 50%)
Common	7.1 - 10 mg
Strong	10 - 15 mg(2x - 50%)
Heavy	15 mg
Extreme	15 mg +

Sublingual []
Light	≤ 3.3 mg(20x - 41.7%)
Common	3.3 - 5 mg(26x - 54.2%)
Strong	5 mg
Heavy	5 mg
Extreme	5 mg +(2x - 4.2%)

Oral []
Light	≤ 5 mg(156x - 49.7%)
Common	5 - 10 mg(136x - 43.3%)
Strong	10 mg
Heavy	10 mg
Extreme	10 mg +(22x - 7%)

Intrarectal []
Light	≤ 30.9 mg(2x - 66.7%)
Common	30.9 mg
Strong	30 - 40 mg
Heavy	40 - 46 mg
Extreme	46 mg +(1x - 33.3%)

Statistically derived dosages via DBI-IGS

We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Dextroamphetamine (also known as amphetamine, Amphetamine, Dexamphetamine, Dexamfetamine, Dexadrine, Dexidrine, (+)-Amphetamine, 1-Phenyl-2-aminopropane, Amsustain or Dephadren) is a stimulant substance of the amphetamine class.

Chemistry

Salts []

Dextroamphetamine is typically found in the form of its hemisaccharate, phosphate, hemisulfate, adipate and hydrochloride salts.

Stereochemistry []

Dextroamphetamine is a absolute mixture.

Pharmacology

ATC Classification

In the nervous system (N) dextroamphetamine acts as a stimulant (N06B), sympathomimetic (N06BA), dexamfetamine (N06BA02) and psychoanaleptic (N06).^[1]

Interactions []

CYP2D6	induction / inhibition

Subjective effects []

class / Stimulant

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

bonzi / Dextroamphetamine []
Routes: Oral (2.5 - 30mg)

0xea / Dextroamphetamine []
Routes: Oral (2.5 - 20mg) Intravenous (5mg) Salts: Sulfate Source: Dexamfetamine sulfate 5mg tablets: Tentin Indication: motivation suppression (executive dysfunction) depression sleepiness cognitive dysphoria Active Effects: strong stimulation strong clean cognitive euphoria strong focus enhancement light vasoconstriction strong compulsive redosing Side Effects: delusion (paranoid, shadow police)

0xea / Dextroamphetamine []

Routes:

Oral (2.5 - 20mg)
Intravenous (5mg)

Salts:

Sulfate

Source:

Dexamfetamine sulfate 5mg tablets: Tentin

Indication:

motivation suppression (executive dysfunction)
depression
sleepiness
cognitive dysphoria

Active Effects:

Side Effects:

delusion (paranoid, shadow police)

Legal status []

Australia: Dextroamphetamine is a S8 substance.^[3]^[4]
Brazil: Dextroamphetamine is a A3 substance.
Canada: Dextroamphetamine is a prescription only substance.
Germany: Dextroamphetamine is a Anlage III substance.
United Kingdom: Dextroamphetamine is a Class B substance.
United States: Dextroamphetamine is a Schedule I under the "Controlled Substances Act (CSA)".
European Union: Dextroamphetamine is a prescription only substance.
United Nations: Dextroamphetamine is a Schedule II drug under the "Convention on Psychotropic Substances 1971".

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 5826, amphetamine. Accessed April 29, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/5826
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Dextroamphetamine. UNII: TZ47U051FI. Global Substance Registration System. Accessed April 29, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/TZ47U051FI
Therapeutic Goods (Poisons Standard—February 2023) Instrument 2022. September 26, 2022. Accessed April 29, 2026. https://www.legislation.gov.au/Series/F2022L01257
Fuller K. ADHD Stimulant Prescribing Regulations & Authorities in Australia & New Zealand. February 20, 2022. Accessed April 29, 2026. https://aadpa.com.au/adhd-stimulant-prescribing-regulations-in-australia-new-zealand/
Adderall- dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablet. February 27, 2022. Accessed April 29, 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f22635fe-821d-4cde-aa12-419f8b53db81
Mignot EJ. A practical guide to the therapy of narcolepsy and hypersomnia syndromes. Neurotherapeutics. October 1, 2012; 9(4):739–752.
Stahl SM. Prescriber's Guide: Stahl's Essential Psychopharmacology. Cambridge University Press. March 1, 2017.

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