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Dextroamphetamine

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Dextroamphetamine
Dextroamphetamine
Salts
[]
Dextroamphetamine hemisaccharate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Dextroamphetamine phosphate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Dextroamphetamine hemisulfate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Dextroamphetamine adipate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Dextroamphetamine hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
135.21 g/mol [1]
Density0.949 g/cu cm at 15 °C g/cm3 [1]
AppearanceColorless liquid [1]
Melting point27.5 °C [1]
Boiling point203.5 °C [1]
DecompositionWhen heated to decomposition it emits toxic nitroxides. [1]
SolubilityModerately Soluble [1]
1.8 [1]
Structural Identifiers
[]
C9H13N [1]
(2S)-1-phenylpropan-2-amine [1]
C[C@@H](CC1=CC=CC=C1)N [1]
InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1 [1]
InChIKeyKWTSXDURSIMDCE-QMMMGPOBSA-N [1]
Pharmacokinetics[]
Elimination half-life9 – 11 hours[5]pH-dependent: 7 – 34 hours
Duration of actionImmediate release dosing: 3 – 6 hours[6]Extended release dosing: 8 – 12 hours[7]
Dosing[]
Insufflated
[]
Light≤ 7.1 mg(2x - 50%)
Common7.1 - 10 mg
Strong10 - 15 mg(2x - 50%)
Heavy15 mg
Extreme15 mg +
Sublingual
[]
Light≤ 3.3 mg(20x - 41.7%)
Common3.3 - 5 mg(26x - 54.2%)
Strong5 mg
Heavy5 mg
Extreme5 mg +(2x - 4.2%)
Oral
[]
Light≤ 5 mg(156x - 49.7%)
Common5 - 10 mg(136x - 43.3%)
Strong10 mg
Heavy10 mg
Extreme10 mg +(22x - 7%)
Intrarectal
[]
Light≤ 30.9 mg(2x - 66.7%)
Common30.9 mg
Strong30 - 40 mg
Heavy40 - 46 mg
Extreme46 mg +(1x - 33.3%)
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Dextroamphetamine (also known as amphetamine, Amphetamine, Dexamphetamine, Dexamfetamine, Dexadrine, Dexidrine, (+)-Amphetamine, 1-Phenyl-2-aminopropane, Amsustain or Dephadren) is a stimulant substance of the amphetamine class.

Chemistry

Salts []

Dextroamphetamine is typically found in the form of its hemisaccharate, phosphate, hemisulfate, adipate and hydrochloride salts.

 []

Dextroamphetamine is a absolute mixture.

Pharmacology

In the () dextroamphetamine acts as a stimulant (), sympathomimetic (), dexamfetamine () and psychoanaleptic ().[1]

Interactions []

induction / inhibition

Subjective effects []

class / Stimulant
bonzi / Dextroamphetamine []
Routes:
  • Oral (2.5 - 30mg)
0xea / Dextroamphetamine []
Routes:
  • Oral (2.5 - 20mg)
  • Intravenous (5mg)
Salts:
  • Sulfate
Source:
  • Dexamfetamine sulfate 5mg tablets: Tentin
Indication:Active Effects:Side Effects:

 []

  • Australia: Dextroamphetamine is a S8 substance.[3][4]
  • Brazil: Dextroamphetamine is a A3 substance.
  • Canada: Dextroamphetamine is a prescription only substance.
  • Germany: Dextroamphetamine is a Anlage III substance.
  • United Kingdom: Dextroamphetamine is a Class B substance.
  • United States: Dextroamphetamine is a Schedule I under the "Controlled Substances Act (CSA)".
  • European Union: Dextroamphetamine is a prescription only substance.
  • United Nations: Dextroamphetamine is a Schedule II drug under the "Convention on Psychotropic Substances 1971".

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 5826, amphetamine. Accessed April 29, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/5826

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Dextroamphetamine. UNII: TZ47U051FI. Global Substance Registration System. Accessed April 29, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/TZ47U051FI

  3. Therapeutic Goods (Poisons Standard—February 2023) Instrument 2022. September 26, 2022. Accessed April 29, 2026. https://www.legislation.gov.au/Series/F2022L01257

  4. Fuller K. ADHD Stimulant Prescribing Regulations & Authorities in Australia & New Zealand. February 20, 2022. Accessed April 29, 2026. https://aadpa.com.au/adhd-stimulant-prescribing-regulations-in-australia-new-zealand/

  5. Adderall- dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablet. February 27, 2022. Accessed April 29, 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f22635fe-821d-4cde-aa12-419f8b53db81

  6. Mignot EJ. A practical guide to the therapy of narcolepsy and hypersomnia syndromes. Neurotherapeutics. October 1, 2012; 9(4):739–752.

  7. Stahl SM. Prescriber's Guide: Stahl's Essential Psychopharmacology. Cambridge University Press. March 1, 2017.