| Heroin | |
|---|---|
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 369.4 g/mol [1] |
| Density | 1.56 g/cu m at 25 °C g/cm3 [1] |
| Appearance | Orthorhombic plates, tablets from ethyl acetate [1] |
| Odor | Odorless [1] |
| Taste | Bitter [1] |
| Melting point | 173 °C [1] |
| Boiling point | 272-274 °C at 1.20E+01 mm Hg [1] |
| Decomposition | ... Decomposes by boiling with water. [1] |
| Solubility | In water, 60 mg/L at 25 °C [1] |
| Predicted LogP | 1.5 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C21H23NO5 [1] |
| IUPAC name | [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl] acetate [1] |
| SMILES | CC(=O)O[C@H]1C=C[C@H]2[C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)OC(=O)C)CCN3C [1] |
| InChI | InChI=1S/C21H23NO5/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20/h4-7,14-15,17,20H,8-10H2,1-3H3/t14-,15+,17-,20-,21-/m0/s1 [1] |
| InChIKey | GVGLGOZIDCSQPN-PVHGPHFFSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 2 – 3 minutes[3] |
| Duration of action | 4 – 5 hours[4] |
| Toxicity [] | |
|---|---|
| LDLo | Mouse: - subcutaneous: 262 mg/kg Dog: - subcutaneous: 25 mg/kg Cat: - oral: 20 mg/kg Guinea pig: - subcutaneous: 400 mg/kg |
| LD50 | Rat: - intravenous: 22500 μg/kg Mouse: - intravenous: 21798 μg/kg - intracrebral: 137 μg/kg |
| Dosing[] |
|---|
| Insufflated [] | |
|---|---|
| Light | ≤ 14 mg |
| Common | 14 - 18 mg |
| Strong | 18 - 25 mg |
| Heavy | 25 - 32.6 mg |
| Extreme | 32.6 mg + |
| Intramuscular [] | |
|---|---|
| Light | ≤ 100 mg |
| Common | 100 mg |
| Strong | 100 mg |
| Heavy | 100 - 160 mg |
| Extreme | 160 mg + |
| Intrarectal [] | |
|---|---|
| Light | ≤ 18.3 mg |
| Common | 18.3 - 22.5 mg |
| Strong | 22.5 - 32 mg |
| Heavy | 32 - 47.2 mg |
| Extreme | 47.2 mg + |
| Vaporized [] | |
|---|---|
| Light | ≤ 33.9 mg |
| Common | 33.9 - 50 mg |
| Strong | 50 - 100 mg |
| Heavy | 100 - 130 mg |
| Extreme | 130 mg + |
Statistically derived dosages via DBI-IGS We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly. |
Diacetylmorphine
Diacetylmorphine (also known as HEROIN, Diamorphine, Acetomorphine, 3,6-Diacetylmorphine, Diaphorm, Eclorion, Morphacetin, O,O'-Diacetylmorphine, Morphine diacetate or Acetomorfine) is a prodrug and opioid substance of the morphinan class.
Chemistry
Stereochemistry []
Diacetylmorphine is a absolute mixture
Pharmacology
Diacetylmorphine acts as a prodrug for:
| Active metabolites [] |
|---|
Subjective effects
| Anodyne Usernotes [] | |
|---|---|
| 0xea / Diacetylmorphine[citrate][ascorbate] via Vaporized and Intravenous |
|
Legal status
- Australia: Diacetylmorphine is a S9 substance.
- Brazil: Diacetylmorphine is a F1 substance.
- Canada: Diacetylmorphine is a Schedule I controlled substance|Schedule I substance.
- Germany: Diacetylmorphine is a Anlage I, Anlage II|II and Anlage III|III substance.
- New Zealand: Diacetylmorphine is a Class A substance.
- United Kingdom: Diacetylmorphine is a Class A substance.
- United States: Diacetylmorphine is a Schedule I under the "Controlled Substances Act (CSA)".
- United Nations: Diacetylmorphine is a Narcotic Schedules I and IV substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 5462328, Diacetylmorphine. Accessed October 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/5462328
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Diacetylmorphine. UNII: 70D95007SX. Global Substance Registration System. Accessed October 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/70D95007SX
Diamorphine Hydrochloride 10mg for Injection. May 6, 2020. Accessed October 13, 2025. https://www.medicines.org.uk/emc/product/1466/smpc
Field J. The Textbook of Emergency Cardiovascular Care and CPR. Lippincott Williams & Wilkins. 2012. Accessed October 13, 2025. https://books.google.com/books?id=o3m4oNRB4D4C&pg=PA447
Anodyne