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Propranolol

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Propranolol
Propranolol
Salts
[]
Propranolol hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
259.34 g/mol [1]
Melting point96 °C [1]
Solubility0.0617 mg/L at 25 °C [1]
3 [1]
Structural Identifiers
[]
C16H21NO2 [1]
1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol [1]
CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O [1]
InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3 [1]
InChIKeyAQHHHDLHHXJYJD-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-life~4 hours (range 3 – 8 hours)
Duration of action12 hours
Dosing[]
Oral
[]
Light≤ 17.5 mg(1x - 50%)
Common17.5 - 25 mg
Strong25 - 32.5 mg
Heavy32.5 - 37 mg
Extreme37 mg +(1x - 50%)
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Propranolol (also known as Propranolol, Propanolol, β-Propranolol, βlong, Euprovasin, Proprasylyt, Reducor, Propanalol, Anapriline or propranololo)

Chemistry

Salts []

Propranolol is typically found in the form of its hydrochloride salt.

 []

Propranolol is a racemic mixture of the .

(R)-PropranololGenerated by the Chemistry Development Kit (http://github.com/cdk)
(S)-PropranololGenerated by the Chemistry Development Kit (http://github.com/cdk)
Stereoisomer enumberation with rdkit

Pharmacology

In the () propranolol acts

Metabolism

Interactions []

CYP2D6induction / inhibition
CYP2C19induction / inhibition
CYP1A2induction / inhibition

Subjective effects []

bonzi / Propranolol []

Legal status []

  • Australia: Propranolol is a S4 substance.
  • Canada: Propranolol is a prescription only substance.
  • United Kingdom: Propranolol is a prescription only substance.
  • United States: Propranolol is a prescription only substance.[3][4][5][6]
  • European Union: Propranolol is a prescription only substance.

See also []

  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 4946, Propranolol. Accessed April 16, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/4946

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Propranolol. UNII: 9Y8NXQ24VQ. Global Substance Registration System. Accessed April 16, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/9Y8NXQ24VQ

    3. Inderal (propranolol hydrochloride) Tablets. Accessed April 16, 2026. https://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=298083

    4. Inderal LA- propranolol hydrochloride capsule, extended release. August 1, 2024. Accessed April 16, 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=35d28979-36b1-4630-b85e-a44e0a443734

    5. Inderal XL- propranolol hydrochloride capsule, extended release. March 20, 2024. Accessed April 16, 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ac196ff5-9215-402b-bc57-69aa87f8bade

    6. Hemangeol- propranolol hydrochloride solution. December 17, 2025. Accessed April 16, 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b6f9dd2a-632b-87eb-70f0-b2064d7ed48a