K | |
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Salts [] | |
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Hydrochloride | |
Molecular structure via molpic based on CDK |
Conformer [] | |
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Conformer structure via JSmol |
Physical properties [] | |
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Molecular mass | 237.72 g/mol [1] |
Appearance | Crystals from pentane-ether [1] |
Melting point | 92.5ºC [1] |
Decomposition | When heated to decomposition it emits toxic fumes of /chloride/ and /nitrogen oxides/. [1] |
Solubility | Soluble [1] |
Predicted LogP | 2.2 [1] |
Structural Identifiers [] | |
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Molecular formula | C13H16ClNO [1] |
IUPAC name | 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one [1] |
SMILES | CNC1(CCCCC1=O)C2=CC=CC=C2Cl [1] |
InChI | InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3 [1] |
InChIKey | YQEZLKZALYSWHR-UHFFFAOYSA-N [1] |
Dosing [] | |
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Elimination half-life | * Ketamine: 2.5 – 3 hours * Norketamine: 12 hours |
Duration of action | * Intramuscular: 0.5 – 2 hours * Insufflation: 45 – 60 min * By mouth: 1 – 6+ hours |
Ketamine
Ketamine (also known as Ketamine, ketamine, Ketaject, Special K, CI 581 base, Calypsol, Ketaminum, CLSTA 20, narketan or Cetamina)
Chemistry
Salts []
Ketamine is typically found in the form of its hydrochloride salt.
Stereochemistry []
Ketamine is a racemic mixture of the optical stereoisomers
Stereoisomers |
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Anodyne Usernotes [] | |
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0xea / Ketamine[hydrochloride] via Insufflated and Intravenous | Unnerving if Injected Rapidly; Body Distortion; Perception in Snap Frames; memory suppression; time distortion; followed by suicidal thoughts; interesting mind manifestation with positive reinforcement |
Experience reports []
There are currently 25+ experience reports involving ketamine on OpenErowid:
- "Tumbling Down the Rabbit Hole" by Big Rig
- "Child of the Sixties Tries K" by Corvin
- "I Wished I Was a Goldfish" by JDIGGS
- "Self-Hatred Fixed" by Shloomth
- "A Lot Stronger and a Lot Harder" by Ant
- "30 Minute Holiday" by fineshrine
- "The Great Light of Enlightenment" by Samuel J
- "Fell Out of a Truck and Into the K-Hole" by A.S
- "Orally It's One Trippy Cat" by Blackmoon
- "Into the K-Hole Unexpectedly" by Old Hippie Dumbass
- "Breaking the Cosmic Holodeck" by Leder
- "I Left Him to the Carpet" by Milky
- "Ket Is for Horses" by Rusty Shackleford
- "Super K" by anon
- "Plugging into the Control Panel" by Bttnkdcatburglar
- "Be Aware. Not Beware..." by problemaftermath
- "Unexpected Results" by Akyouser Oner
- "Vacation From Reality" by Ringo
- "The Binary Ketamine" by Surreal Computers
- "Wow Everything Ever" by The Schwa
- "Going WAY Down The Rabbit K-Hole" by Celestial_
- "Talking With Some Distorted Creatures" by trolest
- "A Nosefull of Knowledge" by Etarded
- "IVing - It's Actually Quite Nice" by KetShooter
- "Existential K Ditch" by ashtray girl
Legal status
- Australia: Ketamine is a S8 substance.
- Brazil: Ketamine is a C1 substance.
- Canada: Ketamine is a Schedule I substance.
- Germany: Ketamine is a prescription only substance.
- United Kingdom: Ketamine is a Class B substance.
- United States: Ketamine is a Schedule I under the "Controlled Substances Act (CSA)".
- United Nations: Ketamine is a Unscheduled substance.
See also []
External links []
- Ketamine / Esketamine / Arketamine (Wikipedia)
- Ketamine / Esketamine / Arketamine (Wikidata)
- Ketamine / Esketamine / Arketamine (DrugBank)
- Ketamine / Esketamine / Arketamine (PubChem)
- Ketamine / Esketamine / Arketamine (ChEMBL)
- Ketamine / Esketamine / Arketamine (ChEBI)
- Ketamine / Esketamine / Arketamine (Common Chemistry)
- Ketamine (HMDB)
- Ketamine / Arketamine (KEGG)
- Ketamine / Esketamine / Arketamine (UNII)
- Ketamine / Esketamine / Arketamine (EPA DSSTox)
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3821, Ketamine. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/3821
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Ketamine. UNII: 690G0D6V8H. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/690G0D6V8H