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Fluoxetine
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
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Physical properties
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309.33 g/mol [1]
Melting point179 - 182 °C [1]
Boiling point395.1°C at 760 mmHg [1]
Solubilityinsoluble [1]
4 [1]
Structural Identifiers
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C17H18F3NO [1]
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine [1]
CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F [1]
InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 [1]
InChIKeyRTHCYVBBDHJXIQ-UHFFFAOYSA-N [1]

Fluoxetine

Fluoxetine (also known as Fluoxetina, Animex-On, Fluoxetin, Fluval, Fluoxetinum, Methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine, N-Methyl-γ-(4-(trifluoromethyl)phenoxy)benzenepropanamine, N-Methyl-3-phenyl-3-((α,α,α-trifluoro-p-tolyl)oxy)propylamine, Benzenepropanamine, N-methyl-γ-(4-(trifluoromethyl)phenoxy)-, (+-)- or n-methyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine) is a serotonin reuptake inhibitor substance of the phenylpropylamine class.

Chemistry

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Fluoxetine is a racemic mixture of the

Stereoisomers
(R)-FluoxetineGenerated by the Chemistry Development Kit (http://github.com/cdk)
(S)-FluoxetineGenerated by the Chemistry Development Kit (http://github.com/cdk)
Anodyne Usernotes
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0xea / Fluoxetine via noted acute effects; long term no notable improvement in quality of life; slight potenciation of lisdexamphetamine through CYP2D6 inhibition

Experience reports []

There are currently 6 experience reports involving fluoxetine on OpenErowid:

See also []

  • Substituted phenylpropylamines
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 3386, Fluoxetine. Accessed August 2, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/3386