Anodyne

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Pemoline
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
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Physical properties
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176.17 g/mol [1]
AppearanceCrystals [1]
TasteTasteless [1]
Melting pointDecomp: 256-257 °C [1]
DecompositionWhen heated to decomposition it emits toxic fumes of /Nitrogen oxide/. [1]
SolubilityPractically insol in ether, acetone, dil hydrochloric acid; sol in propylene glycol (1%) and hot alcohol [1]
0.9 [1]
Structural Identifiers
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C9H8N2O2 [1]
2-amino-5-phenyl-1,3-oxazol-4-one [1]
C1=CC=C(C=C1)C2C(=O)N=C(O2)N [1]
InChI=1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12) [1]
InChIKeyNRNCYVBFPDDJNE-UHFFFAOYSA-N [1]
Dosing
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Elimination half-life7 – 12 hours

Pemoline

Pemoline (also known as Phenoxazole, Phenylisohydantoin, Azoksodon, Fenoxazol, Azoxodon, Dantromin, Cylert, Pemolin, Tradon or Azoxodone) is a substance of the aminorex class.

Chemistry

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Pemoline is a racemic mixture of the optical stereoisomers

Stereoisomers
(+)-PemolineGenerated by the Chemistry Development Kit (http://github.com/cdk)
(-)-PemolineGenerated by the Chemistry Development Kit (http://github.com/cdk)

Legal status []

  • Australia: Pemoline is a S4 substance.
  • Brazil: Pemoline is a B1 substance.[3]
  • Canada: Pemoline is a Schedule IV substance.
  • Germany: Pemoline is a prescription only/Anlage III substance.
  • United States: Pemoline is a Schedule I under the "Controlled Substances Act (CSA)".

See also []

  • Substituted aminorexes
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 4723, Pemoline. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/4723

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Pemoline. UNII: 7GAQ2332NK. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/7GAQ2332NK

    3. Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed July 13, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992