Anodyne

Enable Hints
Enable jsmol
Collapse all
Toggle theme
Lidocaine
Lidocaine
Salts
[]
Lidocaine carbonate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Lidocaine tosylate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Lidocaine bicarbonate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Lidocaine iminodiacetic acid
Generated by the Chemistry Development Kit (http://github.com/cdk)
Lidocaine maleate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Lidocaine hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Lidocaine sulfate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
234.34 g/mol [1]
AppearanceNeedles from benzene or alcohol [1]
OdorCharacteristic odor [1]
Melting point68 °C [1]
Boiling point159-160 °C at 2.00E+00 mm Hg [1]
DecompositionWhen heated to decomposition it emits toxic fumes of /nitrogen oxides/. [1]
SolubilityVERY SOL IN ALC; SOL IN CHLOROFORM; INSOL IN ETHER; WHITE CRYSTALLINE POWDER /LIDOCAINE HYDROCHLORIDE/ [1]
2.3 [1]
Structural Identifiers
[]
C14H22N2O [1]
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide [1]
CCN(CC)CC(=O)NC1=C(C=CC=C1C)C [1]
InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17) [1]
InChIKeyNNJVILVZKWQKPM-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-life1.5 h - 2 h
Duration of action10 min - 20 min (IV), 0.5 h - 3 h (local)

Lidocaine

Lidocaine is a sodium channel blocker substance of the aniline class.

Chemistry

Salts []

Lidocaine is typically found in the form of its carbonate, tosylate, bicarbonate, iminodiacetic acid, maleate, hydrochloride and sulfate salts.

 []

Lidocaine is a achiral mixture

Pharmacology

Interactions []

  • CYP3A4 induction
  • CYP3A4 inhibition
  • CYP1A2 induction
  • CYP3A4 inhibitioninduction
  • CYP1A2 inhibitioninduction
  • CYP1A2 inhibition
Anodyne Usernotes
[]
0xea / Lidocaine[freebase] via Topical
  • numbing effect on rectum; treatment for potencial hemorrhoid

Legal status []

  • Australia: Lidocaine is a S5, S4, and S2 substance.[3]
  • Canada: Lidocaine is a prescription only substance.
  • United Kingdom: Lidocaine is a GSL, P, and prescription only substance.
  • United States: Lidocaine is a prescription only substance.

See also []

  • Substituted anilines
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 3676, Lidocaine. Accessed December 20, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/3676

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Lidocaine. UNII: 98PI200987. Global Substance Registration System. Accessed December 20, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/98PI200987

    3. Poisons Standard February 2021. January 1, 2021. Accessed December 20, 2025. https://www.legislation.gov.au/Details/F2021C00098