{"ATC Code":"N01BB02","Abbreviation":[],"Absorption, Distribution and Excretion":"In general, lidocaine is readily absorbed across mucous membranes and damaged skin but poorly through intact skin. The agent is quickly absorbed from the upper airway, tracheobronchial tree, and alveoli into the bloodstream. And although lidocaine is also well absorbed across the gastrointestinal tract the oral bioavailability is only about 35% as a result of a high degree of first-pass metabolism. After injection into tissues, lidocaine is also rapidly absorbed and the absorption rate is affected by both vascularity and the presence of tissue and fat capable of binding lidocaine in the particular tissues.  The concentration of lidocaine in the blood is subsequently affected by a variety of aspects, including its rate of absorption from the site of injection, the rate of tissue distribution, and the rate of metabolism and excretion. Subsequently, the systemic absorption of lidocaine is determined by the site of injection, the dosage given, and its pharmacological profile. The maximum blood concentration occurs following intercostal nerve blockade followed in order of decreasing concentration, the lumbar epidural space, brachial plexus site, and subcutaneous tissue. The total dose injected regardless of the site is the primary determinant of the absorption rate and blood levels achieved. There is a linear relationship between the amount of lidocaine injected and the resultant peak anesthetic blood levels.  Nevertheless, it has been observed that lidocaine hydrochloride is completely absorbed following parenteral administration, its rate of absorption depending also on lipid solubility and the presence or absence of a vasoconstrictor agent. Except for intravascular administration, the highest blood levels are obtained following intercostal nerve block and the lowest after subcutaneous administration.  Additionally, lidocaine crosses the blood-brain and placental barriers, presumably by passive diffusion.","Adverse Effects":"Most adverse reactions associated with lidocaine occur when plasma concentrations rise to toxic levels. The drug reaches the intravascular compartment most rapidly when administered into the intercostal space, followed by the caudal, epidural, brachial plexus, femoral, and subcutaneous spaces. The maximum safe dose by body weight may range from 3 mg/kg to 7 mg/kg when using formulations containing epinephrine, although various other doses have been documented. Smaller doses can still result in adverse effects and toxicity if administered intravenously. Lidocaine is thought to be more neurotoxic than other local anesthetics, especially when high concentrations are applied directly to nervous tissue. Use of highly concentrated lidocaine (2.5% to 5%) for spinal anesthesia correlates with a greater incidence of transient radicular irritation syndrome, which is a painful but self-limiting condition affecting the calves, thighs, and buttocks.","Biological Half-Life":"The elimination half-life of lidocaine hydrochloride following an intravenous bolus injection is typically 1.5 to 2.0 hours. Because of the rapid rate at which lidocaine hydrochloride is metabolized, any condition that affects liver function may alter lidocaine HCl kinetics. The half-life may be prolonged two-fold or more in patients with liver dysfunction.","Boiling Point":"159-160 °C at 2.00E+00 mm Hg","CAS":"137-58-6","Chemical Classes":"Pharmaceutical","ChemicalClasses":["aniline"],"Chirality":"achiral","Classes":["Sodium channel blocker"],"Color/Form":"Needles from benzene or alcohol","Decomposition":"When heated to decomposition it emits toxic fumes of /nitrogen oxides/.","Drug Classes":["Breast Feeding","Lactation","Milk, Human","Antiarrhythmics","Local Anesthetics"],"Drug Indication":"Lidocaine is an anesthetic of the amide group indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.","Drug Warnings":"WARNING: Life-threatening and fatal events in infants and young children. Postmarketing cases of seizures, cardiopulmonary arrest, and death in patients under the age of 3 years have been reported with use of Xylocaine 2% Viscous Solution when it was not administered in strict adherence to the dosing and administration recommendations. In the setting of teething pain, Xylocaine 2% Viscous Solution should generally not be used. For other conditions, the use of the product in patients less than 3 years of age should be limited to those situations where safer alternatives are not available or have been tried but failed. To decrease the risk of serious adverse events with use of Xylocaine 2% Viscous Solution, instruct caregivers to strictly adhere to the prescribed dose and frequency of administration and store the prescription bottle safely out of reach of children.","DurationOfAction":"10\u0026nbsp;min - 20\u0026nbsp;min (IV), 0.5\u0026nbsp;h - 3\u0026nbsp;h (local)","Ecotoxicity Values":"EC50; Species: Chlorella fusca var. vacuolata (Green Algae) strain 211-15; Conditions: freshwater, static, 25 °C, pH 9.5-10.0; Concentration: 459 uM for 24 hr (95% confidence interval: 158-1333 uM); Effect: decreased population growth rate /formulation/","EliminationHalfLife":"1.5\u0026nbsp;h - 2\u0026nbsp;h","Esters":[],"European Community (EC) Number":"205-302-8","FDA Pharmacological Classification":"98PI200987","Formating":[],"HMDB ID":"HMDB0014426","Health Effects":"Systemic exposure to excessive quantities of lidocaine mainly result in central nervous system (CNS) and cardiovascular effects. CNS effects may include CNS excitation(nervousness, tingling around the mouth) followed by depression. [Wikipedia]","HeavyAtomCount":17,"Human Drugs":"Breast Feeding; Lactation; Milk, Human; Antiarrhythmics; Local Anesthetics","IUPACName":"2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide","InChI":"InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)","InChIKey":"NNJVILVZKWQKPM-UHFFFAOYSA-N","Interactions":"EMLA cream is a topical formulation based upon the eutectic mixture of lidocaine and prilocaine and is used in clinical settings to produce local analgesia after application under occlusive dressing. A blanching reaction has been reported to occur locally after application, but it is not clear whether this reaction is caused by the anesthetic mixture, by the vehicle or the occlusion. This blanching reaction was studied in 50 healthy volunteers in a double-blind randomized assay: EMLA versus placebo, under occlusive dressing for 1 hr, each subject being his own control. 33 Cases (66%) of blanching after application of EMLA cream were observed versus 3 cases (6%) after placebo, this difference being highly significant. Blanching was observed without delay, after removal of the dressing, and was very transient, disappearing in less than 3 hr in all cases. It is concluded that the blanching reaction is (1) frequent but very transient, and (2) determined by the anesthetic mixture included in EMLA cream and not by the vehicle alone, nor by the occlusion, since it is not found with the placebo. The precise mechanism of this reaction is unknown.","KEGG Entries":[{"Id":"D00358","Interactions":[{"Action":"induction","Target":"CYP3A4"},{"Action":"inhibition","Target":"CYP3A4"},{"Action":"induction","Target":"CYP1A2"},{"Action":"inhibitioninduction","Target":"CYP3A4"},{"Action":"inhibitioninduction","Target":"CYP1A2"},{"Action":"inhibition","Target":"CYP1A2"}],"Synonyms":["Lidocaine","Dentipatch","Xylocaine"]},{"Id":"D02086","Interactions":[{"Action":"induction","Target":"CYP3A4"},{"Action":"inhibition","Target":"CYP3A4"},{"Action":"induction","Target":"CYP1A2"},{"Action":"inhibitioninduction","Target":"CYP3A4"},{"Action":"inhibitioninduction","Target":"CYP1A2"},{"Action":"inhibition","Target":"CYP1A2"}],"Synonyms":["Lidocaine hydrochloride","Dalcaine","Xylocaine"]},{"Id":"D02740","Interactions":[{"Action":"induction","Target":"CYP3A4"},{"Action":"inhibition","Target":"CYP3A4"},{"Action":"inhibitioninduction","Target":"CYP3A4"},{"Action":"inhibitioninduction","Target":"CYP1A2"},{"Action":"inhibition","Target":"CYP1A2"}],"Synonyms":["Lidocaine and prilocaine","Lidocaine and propitocaine","Emla","Oraqix"]},{"Id":"D04052","Interactions":[{"Action":"induction","Target":"CYP3A4"},{"Action":"inhibition","Target":"CYP3A4"},{"Action":"inhibition","Target":"CYP1A2"},{"Action":"inhibitioninduction","Target":"CYP3A4"},{"Action":"inhibitioninduction","Target":"CYP1A2"}],"Synonyms":["Epinephrine and lidocaine hydrochloride","Adrenaline and lidocaine hydrochloride","Xylocaine"]},{"Id":"D04688","Interactions":[],"Synonyms":["Tribenoside and lidocaine","Borraza-G"]},{"Id":"D04692","Interactions":[],"Synonyms":["Diflucortolone valerate and lidocaine","Neriproct"]},{"Id":"D04813","Interactions":[{"Action":"induction","Target":"CYP3A4"},{"Action":"inhibition","Target":"CYP3A4"},{"Action":"inhibitioninduction","Target":"CYP3A4"},{"Action":"inhibitioninduction","Target":"CYP1A2"},{"Action":"inhibition","Target":"CYP1A2"}],"Synonyms":["Lidocaine hydrochloride and epinephrine bitartrate","Lidocaine hydrochloride and adrenaline bitartrate","Ora","Lidosite"]},{"Id":"D04881","Interactions":[],"Synonyms":["Aluminum chloride, cetylpyridinium chloride and Lidocaine","Dental TDZ"]},{"Id":"D07742","Interactions":[],"Synonyms":["Ethyl aminobenzoate, lidocaine and bismuth subgallate","Helmitin S"]},{"Id":"D08127","Interactions":[{"Action":"induction","Target":"CYP3A4"},{"Action":"inhibition","Target":"CYP3A4"},{"Action":"induction","Target":"CYP1A2"},{"Action":"inhibitioninduction","Target":"CYP3A4"},{"Action":"inhibitioninduction","Target":"CYP1A2"},{"Action":"inhibition","Target":"CYP1A2"}],"Synonyms":["Lidocaine hydrochloride monohydrate","Lidocaine","Zingo"]},{"Id":"D11553","Interactions":[{"Action":"inhibition","Target":"CYP1A2"}],"Synonyms":["Lidocaine and tetracaine","Pliaglis","Synera"]}],"MeSH Pharmacological Classification":"Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman\u0026apos;s The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.","Mechanism of Action":"Lidocaine is a local anesthetic of the amide type. It is used to provide local anesthesia by nerve blockade at various sites in the body. It does so by stabilizing the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action. In particular, the lidocaine agent acts on sodium ion channels located on the internal surface of nerve cell membranes. At these channels, neutral uncharged lidocaine molecules diffuse through neural sheaths into the axoplasm where they are subsequently ionized by joining with hydrogen ions. The resultant lidocaine cations are then capable of reversibly binding the sodium channels from the inside, keeping them locked in an open state that prevents nerve depolarization. As a result, with sufficient blockage, the membrane of the postsynaptic neuron will ultimately not depolarize and will thus fail to transmit an action potential. This facilitates an anesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their generation in the first place.  In addition to blocking conduction in nerve axons in the peripheral nervous system, lidocaine has important effects on the central nervous system and cardiovascular system. After absorption, lidocaine may cause stimulation of the CNS followed by depression and in the cardiovascular system, it acts primarily on the myocardium where it may produce decreases in electrical excitability, conduction rate, and force of contraction.","Melting Point":"68 °C","Metabolism/Metabolites":"Lidocaine is metabolized predominantly and rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of lidocaine HCl. Approximately 90% of lidocaine HCl administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.","MolecularFormula":"C\u003csub\u003e14\u003c/sub\u003eH\u003csub\u003e22\u003c/sub\u003eN\u003csub\u003e2\u003c/sub\u003eO","MolecularWeight":"234.34 g/mol","Non-Human Toxicity Values":"LD50 Mouse oral 292 mg/kg","Odor":"Characteristic odor","Pharmacodynamics":"Excessive blood levels of lidocaine can cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. With central neural blockade these changes may be attributable to the block of autonomic fibers, a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system, and/or the beta-adrenergic receptor stimulating action of epinephrine when present. The net effect is normally a modest hypotension when the recommended dosages are not exceeded.  In particular, such cardiac effects are likely associated with the principal effect that lidocaine elicits when it binds and blocks sodium channels, inhibiting the ionic fluxes required for the initiation and conduction of electrical action potential impulses necessary to facilitate muscle contraction. Subsequently, in cardiac myocytes, lidocaine can potentially block or otherwise slow the rise of cardiac action potentials and their associated cardiac myocyte contractions, resulting in possible effects like hypotension, bradycardia, myocardial depression, cardiac arrhythmias, and perhaps cardiac arrest or circulatory collapse.  Moreover, lidocaine possesses a dissociation constant (pKa) of 7.7 and is considered a weak base. As a result, about 25% of lidocaine molecules will be un-ionized and available at the physiological pH of 7.4 to translocate inside nerve cells, which means lidocaine elicits an onset of action more rapidly than other local anesthetics that have higher pKa values. This rapid onset of action is demonstrated in about one minute following intravenous injection and fifteen minutes following intramuscular injection. The administered lidocaine subsequently spreads rapidly through the surrounding tissues and the anesthetic effect lasts approximately ten to twenty minutes when given intravenously and about sixty to ninety minutes after intramuscular injection.  Nevertheless, it appears that the efficacy of lidocaine may be minimized in the presence of inflammation. This effect could be due to acidosis decreasing the amount of un-ionized lidocaine molecules, a more rapid reduction in lidocaine concentration as a result of increased blood flow, or potentially also because of increased production of inflammatory mediators like peroxynitrite that elicit direct actions on sodium channels.","Physical Description":"Solid","PubChemId":3676,"Records":{"UNII":{"Impurities":["2-(isopropylamino)-2',6'-acetoxylidide","n-acetyl-2,6-xylidine","2,2'-iminobis(n-(2,6-dimethylphenyl)acetamide)","2-diethylamino-2',5'-acetoxylidide","2-diethylamino-2',3'-acetoxylidide","2,6-xylidine","2-(diethylamino)-2',4'-acetoxylidide","lidocaine n2-oxide","2-chloro-2',6'-acetoxylidide","norlidocaine"]}},"RefCount":4,"RefCur":"","References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Lidocaine","Name":"Lidocaine","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q216935","Name":"Lidocaine","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB00281","Name":"Lidocaine","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/3676","Name":"Lidocaine","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=137-58-6","Name":"Lidocaine","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0014426","Name":"Lidocaine","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C07073","Name":"Lidocaine","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/98PI200987","Name":"Lidocaine","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID1045166","Name":"Lidocaine","Sub":false}]}],"Refs":["National Center for Biotechnology Information. PubChem Compound Summary for CID 3676, Lidocaine. Accessed December 20, 2025. \u003ca href=https://pubchem.ncbi.nlm.nih.gov/compound/3676\u003ehttps://pubchem.ncbi.nlm.nih.gov/compound/3676\u003c/a\u003e","U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Lidocaine. UNII: 98PI200987. Global Substance Registration System. Accessed December 20, 2025. \u003ca href=https://gsrs.ncats.nih.gov/ginas/app/beta/substances/98PI200987\u003ehttps://gsrs.ncats.nih.gov/ginas/app/beta/substances/98PI200987\u003c/a\u003e","Poisons Standard February 2021. January 1, 2021. Accessed December 20, 2025. \u003ca href=https://www.legislation.gov.au/Details/F2021C00098\u003ehttps://www.legislation.gov.au/Details/F2021C00098\u003c/a\u003e"],"Reported Fatal Dose":"Two fatal cases of deliberate self poisoning with lignocaine are reported, one by oral ingestion and one by iv injection. Post-mortem blood lignocaine concn were 40 and 53 mg/L, respectively.","SMILES":"CCN(CC)CC(=O)NC1=C(C=CC=C1C)C","SaltData":[{"AcidCount":1,"Amine":"Lidocaine","AmineCount":1,"Formula":"C(=O)(O)O","Name":"carbonate","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 156.388 47.685\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h157v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m106.629 23.779-13.198-7.62M93.431 16.159l-10.045 5.799M80.232 27.628v11.391M80.232 39.019l13.199 7.62M77.079 21.958l-10.045-5.799M67.034 16.159l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M55.055 23.075v12.022M52.617 23.075v12.022\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M55.055 35.097v-6.011M52.617 35.097v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.779-10.045-5.8M37.484 17.979l-10.044 5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 39.027-.004-15.248M25.006 37.619l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 39.027-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 39.019 13.203 7.628M3.481 37.611l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"M1.043 39.019 1.038 23.77\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M14.236 16.15 1.038 23.77M14.236 18.966 3.477 25.178\"/\u003e\u003c/g\u003e\u003cpath d=\"M27.44 23.779 14.236 16.15M14.236 16.15 14.239.91M27.444 39.027l13.2 7.618\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M82.173 26.228h-.72l-2.62-4.066h-.029l.029.596q.024.357.024.732v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.327-.023-.477q-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M56.095 39.016q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875t.256 1.328m-3.863 0q0 .922.387 1.458.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 18.608h-.72l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.577zM42.442 13.147h-.62v-2.286H39.31v2.286h-.613V8.248h.613v2.071h2.512V8.248h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m83.386 21.958 5.023-2.9M80.232 27.628v5.695M77.079 21.958l-5.023-2.9M43.791 17.979l5.022 2.9M43.791 17.979l5.022 2.9M37.484 17.979l-5.022 2.9M37.484 17.979l-5.022 2.9\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m140.371 26.245 10.524 6.076M139.151 28.357l10.524 6.076\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m150.895 32.321-5.262-3.038M149.675 34.433l-5.262-3.038\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m140.371 27.653-9.92 5.727M140.371 27.653V16.334\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M155.828 35.27q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.863 0q0 .922.386 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524-.392.524-.392 1.453\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M129.432 35.27q0 .756-.256 1.327-.256.566-.756.881t-1.245.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.733 0 1.233.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M124.352 37.722h-.62v-2.286h-2.512v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.62z\"/\u003e\u003c/g\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M142.63 12.41q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.245-.571-.245-1.333 0-.75.245-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.453M146.936 14.862h-.619v-2.286h-2.512v2.286h-.613V9.963h.613v2.072h2.512V9.963h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m130.451 33.38 4.96-2.863M130.451 33.38l4.96-2.863M140.371 16.334v5.659M140.371 16.334v5.659\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Lidocaine carbonate","UNII":"F0783GVP2Z"},{"AcidCount":1,"Amine":"Lidocaine","AmineCount":1,"Formula":"Cc1ccc(cc1)S(=O)(=O)O","Name":"tosylate","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 189.911 47.801\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h190v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m106.629 23.836-13.198-7.62M93.431 16.216l-10.045 5.8M80.232 27.686v11.39M80.232 39.076l13.199 7.62M77.079 22.016l-10.045-5.8M67.034 16.216l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M55.055 23.132v12.023M52.617 23.132v12.023\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M55.055 35.155v-6.011M52.617 35.155v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.836-10.045-5.799M37.484 18.037 27.44 23.836\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 39.085-.004-15.249M25.006 37.677l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 39.085-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 39.076 13.203 7.629M3.481 37.669l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"m1.043 39.076-.005-15.248\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m14.236 16.208-13.198 7.62M14.236 19.024 3.477 25.235\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.44 23.836-13.204-7.628M14.236 16.208l.003-15.24M27.444 39.085l13.2 7.618\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M82.173 26.286h-.72l-2.62-4.066h-.029l.029.595q.024.357.024.733v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.328-.023-.476q-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M56.095 39.073q0 .756-.256 1.328-.256.565-.756.881-.5.315-1.244.315-.756 0-1.262-.315-.506-.316-.756-.887-.244-.572-.244-1.334 0-.75.244-1.309.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875.256.565.256 1.327m-3.863 0q0 .923.387 1.459.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.459 0-.928-.387-1.452-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.452\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 18.666h-.72L39.239 14.6h-.03l.03.595q.024.357.024.733v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.328-.024-.476q-.006-.262-.006-.482v-2.768h.577zM42.442 13.205h-.62v-2.286H39.31v2.286h-.613v-4.9h.613v2.072h2.512V8.305h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m83.386 22.016 5.023-2.9M80.232 27.686v5.695M77.079 22.016l-5.023-2.9M43.791 18.037l5.022 2.899M43.791 18.037l5.022 2.899M37.484 18.037l-5.022 2.899M37.484 18.037l-5.022 2.899\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"M188.873 1.038 175.676 8.66\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m175.676 8.66-13.208-7.62M173.238 10.069l-10.77-6.214\"/\u003e\u003c/g\u003e\u003cpath d=\"M162.468 1.04 149.26 8.66\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M149.26 8.66V23.9M151.699 10.069v12.423\"/\u003e\u003c/g\u003e\u003cpath d=\"m149.26 23.9 13.208 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m162.468 31.52 13.208-7.62M162.468 28.705l10.77-6.213\"/\u003e\u003c/g\u003e\u003cpath d=\"M175.676 8.66V23.9M149.26 23.9l-10.5 6.065\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m133.93 34.162-7.176 4.145M132.711 32.051l-7.177 4.145\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m133.93 34.162-3.588 2.072\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m126.754 38.307 3.588-2.073\" class=\"hi\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m132.711 32.051-3.588 2.072\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m125.534 36.196 3.589-2.073\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m139.01 34.186 3.761 6.512M136.898 35.405l3.761 6.513\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m139.01 34.186 1.88 3.256\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m142.771 40.698-1.881-3.256\" class=\"hi\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m136.898 35.405 1.881 3.257\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m140.659 41.918-1.88-3.256\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m134.169 28.243-3.761-6.512\" class=\"bond\"/\u003e\u003cpath fill=\"#c6c62c\" stroke=\"none\" d=\"M137.608 32.659q0 .649-.476 1.018-.47.364-1.268.364-.417 0-.768-.066-.345-.059-.578-.173v-.589q.245.113.608.203.369.089.762.089.547 0 .827-.215.28-.214.28-.577 0-.238-.107-.399-.101-.167-.351-.309-.25-.143-.697-.298-.625-.226-.947-.554-.315-.333-.315-.899 0-.393.196-.666.203-.28.554-.429.357-.155.816-.155.404 0 .738.078.339.071.613.196l-.196.53q-.25-.113-.548-.185-.298-.077-.625-.077-.459 0-.691.196-.232.197-.232.518 0 .244.101.411.107.167.34.298.232.125.631.28.428.154.726.339.298.178.452.434.155.251.155.637\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M125.125 39.142q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875t.256 1.328m-3.863 0q0 .922.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M145.945 44.716q0 .756-.256 1.328-.256.566-.756.881-.501.316-1.245.316-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.751.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.233.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.459 0-.928-.387-1.452-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.452\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M130.7 18.322q0 .756-.256 1.328-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.751.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875.256.565.256 1.327m-3.863 0q0 .923.387 1.459.393.53 1.22.53.84 0 1.221-.53.386-.536.386-1.459 0-.928-.386-1.452-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.452M125.62 20.775h-.619v-2.286h-2.512v2.286h-.613v-4.899h.613v2.071h2.512v-2.071h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#c6c62c\" d=\"m138.76 29.965 5.25-3.033M134.169 28.243l-1.881-3.256\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m130.408 21.731 1.88 3.256M130.408 21.731l1.88 3.256\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Lidocaine tosylate","UNII":"M0335SFO80"},{"AcidCount":1,"Amine":"Lidocaine","AmineCount":1,"Formula":"C(=O)(O)O","Name":"bicarbonate","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 156.388 47.685\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h157v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m106.629 23.779-13.198-7.62M93.431 16.159l-10.045 5.799M80.232 27.628v11.391M80.232 39.019l13.199 7.62M77.079 21.958l-10.045-5.799M67.034 16.159l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M55.055 23.075v12.022M52.617 23.075v12.022\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M55.055 35.097v-6.011M52.617 35.097v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.779-10.045-5.8M37.484 17.979l-10.044 5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 39.027-.004-15.248M25.006 37.619l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 39.027-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 39.019 13.203 7.628M3.481 37.611l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"M1.043 39.019 1.038 23.77\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M14.236 16.15 1.038 23.77M14.236 18.966 3.477 25.178\"/\u003e\u003c/g\u003e\u003cpath d=\"M27.44 23.779 14.236 16.15M14.236 16.15 14.239.91M27.444 39.027l13.2 7.618\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M82.173 26.228h-.72l-2.62-4.066h-.029l.029.596q.024.357.024.732v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.327-.023-.477q-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M56.095 39.016q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875t.256 1.328m-3.863 0q0 .922.387 1.458.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 18.608h-.72l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.577zM42.442 13.147h-.62v-2.286H39.31v2.286h-.613V8.248h.613v2.071h2.512V8.248h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m83.386 21.958 5.023-2.9M80.232 27.628v5.695M77.079 21.958l-5.023-2.9M43.791 17.979l5.022 2.9M43.791 17.979l5.022 2.9M37.484 17.979l-5.022 2.9M37.484 17.979l-5.022 2.9\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m140.371 26.245 10.524 6.076M139.151 28.357l10.524 6.076\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m150.895 32.321-5.262-3.038M149.675 34.433l-5.262-3.038\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m140.371 27.653-9.92 5.727M140.371 27.653V16.334\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M155.828 35.27q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.863 0q0 .922.386 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524-.392.524-.392 1.453\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M129.432 35.27q0 .756-.256 1.327-.256.566-.756.881t-1.245.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.733 0 1.233.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M124.352 37.722h-.62v-2.286h-2.512v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.62z\"/\u003e\u003c/g\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M142.63 12.41q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.245-.571-.245-1.333 0-.75.245-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.453M146.936 14.862h-.619v-2.286h-2.512v2.286h-.613V9.963h.613v2.072h2.512V9.963h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m130.451 33.38 4.96-2.863M130.451 33.38l4.96-2.863M140.371 16.334v5.659M140.371 16.334v5.659\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Lidocaine bicarbonate","UNII":"2DO9G6G1JY"},{"AcidCount":1,"Amine":"Lidocaine","AmineCount":1,"Formula":"C(C(=O)O)NCC(=O)O","Name":"iminodiacetic acid","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 209.181 47.685\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h210v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m106.629 23.779-13.198-7.62M93.431 16.159l-10.045 5.799M80.232 27.628v11.391M80.232 39.019l13.199 7.62M77.079 21.958l-10.045-5.799M67.034 16.159l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M55.055 23.075v12.022M52.617 23.075v12.022\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M55.055 35.097v-6.011M52.617 35.097v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.779-10.045-5.8M37.484 17.979l-10.044 5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 39.027-.004-15.248M25.006 37.619l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 39.027-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 39.019 13.203 7.628M3.481 37.611l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"M1.043 39.019 1.038 23.77\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M14.236 16.15 1.038 23.77M14.236 18.966 3.477 25.178\"/\u003e\u003c/g\u003e\u003cpath d=\"M27.44 23.779 14.236 16.15M14.236 16.15 14.239.91M27.444 39.027l13.2 7.618\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M82.173 26.228h-.72l-2.62-4.066h-.029l.029.596q.024.357.024.732v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.327-.023-.477q-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M56.095 39.016q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875t.256 1.328m-3.863 0q0 .922.387 1.458.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 18.608h-.72l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.577zM42.442 13.147h-.62v-2.286H39.31v2.286h-.613V8.248h.613v2.071h2.512V8.248h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m83.386 21.958 5.023-2.9M80.232 27.628v5.695M77.079 21.958l-5.023-2.9M43.791 17.979l5.022 2.9M43.791 17.979l5.022 2.9M37.484 17.979l-5.022 2.9M37.484 17.979l-5.022 2.9\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m179.965 35.273 13.199-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m193.164 26.245 10.524 6.076M191.944 28.357l10.524 6.076\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m203.688 32.321-5.262-3.038M202.468 34.433l-5.262-3.038\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"M193.164 27.653V16.334M179.965 35.273l-10.045-5.8M163.614 29.473l-10.045 5.8M153.569 35.273l-13.198-7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M139.151 28.357V16.334M141.59 28.357V16.334\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M139.151 16.334v6.012M141.59 16.334v6.012\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m140.371 27.653-9.92 5.727\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M208.621 35.27q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.453\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M195.423 12.41q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.263-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881.507-.316 1.274-.316.733 0 1.233.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M199.729 14.862h-.619v-2.286h-2.512v2.286h-.614V9.963h.614v2.072h2.512V9.963h.619z\"/\u003e\u003c/g\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M168.708 30.102h-.72l-2.62-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.715l2.607 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.578zM168.571 24.641h-.619v-2.286h-2.512v2.286h-.614v-4.899h.614v2.071h2.512v-2.071h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"none\" d=\"M142.63 12.41q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.245-.571-.245-1.333 0-.75.245-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.453\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M129.432 35.27q0 .756-.256 1.327-.256.566-.756.881t-1.245.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.733 0 1.233.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M124.352 37.722h-.62v-2.286h-2.512v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M193.164 16.334v5.659M193.164 16.334v5.659\" class=\"hi\"/\u003e\u003cpath stroke=\"#3050f8\" d=\"m169.92 29.473 5.022 2.9M169.92 29.473l5.022 2.9M163.614 29.473l-5.023 2.9M163.614 29.473l-5.023 2.9\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m130.451 33.38 4.96-2.863M130.451 33.38l4.96-2.863\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Lidocaine iminodiacetic acid","UNII":"FAO4HZ1165"},{"AcidCount":1,"Amine":"Lidocaine","AmineCount":1,"Formula":"O=C(O)CC(O)C(=O)O","Name":"maleate","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 195.983 47.685\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h196v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m106.629 23.779-13.198-7.62M93.431 16.159l-10.045 5.799M80.232 27.628v11.391M80.232 39.019l13.199 7.62M77.079 21.958l-10.045-5.799M67.034 16.159l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M55.055 23.075v12.022M52.617 23.075v12.022\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M55.055 35.097v-6.011M52.617 35.097v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.779-10.045-5.8M37.484 17.979l-10.044 5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 39.027-.004-15.248M25.006 37.619l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 39.027-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 39.019 13.203 7.628M3.481 37.611l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"M1.043 39.019 1.038 23.77\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M14.236 16.15 1.038 23.77M14.236 18.966 3.477 25.178\"/\u003e\u003c/g\u003e\u003cpath d=\"M27.44 23.779 14.236 16.15M14.236 16.15 14.239.91M27.444 39.027l13.2 7.618\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M82.173 26.228h-.72l-2.62-4.066h-.029l.029.596q.024.357.024.732v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.327-.023-.477q-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M56.095 39.016q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875t.256 1.328m-3.863 0q0 .922.387 1.458.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 18.608h-.72l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.577zM42.442 13.147h-.62v-2.286H39.31v2.286h-.613V8.248h.613v2.071h2.512V8.248h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m83.386 21.958 5.023-2.9M80.232 27.628v5.695M77.079 21.958l-5.023-2.9M43.791 17.979l5.022 2.9M43.791 17.979l5.022 2.9M37.484 17.979l-5.022 2.9M37.484 17.979l-5.022 2.9\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m189.27 26.813-10.524-6.076M190.489 24.701l-10.524-6.076\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m189.27 26.813-5.262-3.038M190.489 24.701l-5.262-3.038\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"M179.965 20.033V8.714M179.965 20.033l-13.198 7.62M166.767 27.653l-13.198-7.62M153.569 20.033V8.714M153.569 20.033l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M141.59 26.949v12.022M139.151 26.949v12.022\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M141.59 38.971V32.96M139.151 38.971V32.96\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m140.371 27.653-9.923-5.729\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M195.423 27.65q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.263-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881.507-.316 1.274-.316.733 0 1.233.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M182.225 4.79q0 .756-.256 1.327-.256.566-.756.881-.501.316-1.245.316-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.732 0 1.233.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M186.531 7.242h-.619V4.956h-2.513v2.286h-.613V2.343h.613v2.072h2.513V2.343h.619z\"/\u003e\u003c/g\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M155.828 4.79q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.863 0q0 .922.386 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524-.392.524-.392 1.453M160.134 7.242h-.619V4.956h-2.512v2.286h-.613V2.343h.613v2.072h2.512V2.343h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"none\" d=\"M142.63 42.89q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.245-.571-.245-1.333 0-.75.245-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.453\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M129.432 20.03q0 .756-.256 1.327-.256.566-.756.881t-1.245.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.733 0 1.233.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M124.352 22.482h-.62v-2.286h-2.512v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M179.965 8.714v5.659M179.965 8.714v5.659M153.569 8.714v5.659M153.569 8.714v5.659M130.448 21.924l4.962 2.864M130.448 21.924l4.962 2.864\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Lidocaine maleate","UNII":"1WNS1NP35X"},{"AcidCount":1,"Amine":"Lidocaine","AmineCount":1,"Formula":"Cl","Name":"hydrochloride","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 130.575 47.685\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h131v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m106.629 23.779-13.198-7.62M93.431 16.159l-10.045 5.799M80.232 27.628v11.391M80.232 39.019l13.199 7.62M77.079 21.958l-10.045-5.799M67.034 16.159l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M55.055 23.075v12.022M52.617 23.075v12.022\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M55.055 35.097v-6.011M52.617 35.097v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.779-10.045-5.8M37.484 17.979l-10.044 5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 39.027-.004-15.248M25.006 37.619l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 39.027-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 39.019 13.203 7.628M3.481 37.611l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"M1.043 39.019 1.038 23.77\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M14.236 16.15 1.038 23.77M14.236 18.966 3.477 25.178\"/\u003e\u003c/g\u003e\u003cpath d=\"M27.44 23.779 14.236 16.15M14.236 16.15 14.239.91M27.444 39.027l13.2 7.618\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M82.173 26.228h-.72l-2.62-4.066h-.029l.029.596q.024.357.024.732v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.327-.023-.477q-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M56.095 39.016q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875t.256 1.328m-3.863 0q0 .922.387 1.458.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 18.608h-.72l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.577zM42.442 13.147h-.62v-2.286H39.31v2.286h-.613V8.248h.613v2.071h2.512V8.248h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m83.386 21.958 5.023-2.9M80.232 27.628v5.695M77.079 21.958l-5.023-2.9M43.791 17.979l5.022 2.9M43.791 17.979l5.022 2.9M37.484 17.979l-5.022 2.9M37.484 17.979l-5.022 2.9\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cg fill=\"#1ff01f\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M127.259 21.991q-.786 0-1.238.53-.453.524-.453 1.447 0 .91.417 1.446.422.53 1.268.53.321 0 .607-.054.292-.059.566-.142v.535q-.274.102-.566.149-.292.054-.696.054-.745 0-1.251-.31-.5-.309-.75-.875-.25-.571-.25-1.339 0-.744.268-1.31.274-.566.804-.881.53-.322 1.28-.322.78 0 1.351.286l-.244.524q-.226-.101-.506-.184-.274-.084-.607-.084m2.756 4.423h-.601v-5.215h.601zM124.352 26.414h-.62v-2.286h-2.512v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.62z\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Lidocaine hydrochloride","UNII":"V13007Z41A"},{"AcidCount":1,"Amine":"Lidocaine","AmineCount":1,"Formula":"OS(=O)(=O)O","Name":"sulfate","Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 156.388 47.685\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#ff0d0d\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h157v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m106.629 23.779-13.198-7.62M93.431 16.159l-10.045 5.799M80.232 27.628v11.391M80.232 39.019l13.199 7.62M77.079 21.958l-10.045-5.799M67.034 16.159l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M55.055 23.075v12.022M52.617 23.075v12.022\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M55.055 35.097v-6.011M52.617 35.097v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.779-10.045-5.8M37.484 17.979l-10.044 5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 39.027-.004-15.248M25.006 37.619l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 39.027-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 39.019 13.203 7.628M3.481 37.611l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"M1.043 39.019 1.038 23.77\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M14.236 16.15 1.038 23.77M14.236 18.966 3.477 25.178\"/\u003e\u003c/g\u003e\u003cpath d=\"M27.44 23.779 14.236 16.15M14.236 16.15 14.239.91M27.444 39.027l13.2 7.618\" class=\"bond\"/\u003e\u003cpath fill=\"#3050f8\" stroke=\"none\" d=\"M82.173 26.228h-.72l-2.62-4.066h-.029l.029.596q.024.357.024.732v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.327-.023-.477q-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M56.095 39.016q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875t.256 1.328m-3.863 0q0 .922.387 1.458.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg fill=\"#3050f8\" stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 18.608h-.72l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.577zM42.442 13.147h-.62v-2.286H39.31v2.286h-.613V8.248h.613v2.071h2.512V8.248h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m83.386 21.958 5.023-2.9M80.232 27.628v5.695M77.079 21.958l-5.023-2.9M43.791 17.979l5.022 2.9M43.791 17.979l5.022 2.9M37.484 17.979l-5.022 2.9M37.484 17.979l-5.022 2.9\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m130.451 29.57 7.177-4.144\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m142.458 21.23 7.22-4.169M143.677 23.342l7.221-4.169\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m142.458 21.23 3.61-2.085\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m149.678 17.061-3.61 2.084\" class=\"hi\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m143.677 23.342 3.61-2.084\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m150.898 19.173-3.611 2.085\" class=\"hi\"/\u003e\u003c/g\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m137.421 21.173-3.76-6.513M139.533 19.954l-3.76-6.513\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m137.421 21.173-1.88-3.257\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m133.661 14.66 1.88 3.256\" class=\"hi\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m139.533 19.954-1.88-3.256\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m135.773 13.441 1.88 3.257\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m142.261 27.116 3.76 6.513\" class=\"bond\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M129.432 31.46q0 .756-.256 1.327-.256.566-.756.881t-1.245.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.733 0 1.233.316.5.31.756.875.256.566.256 1.328m-3.864 0q0 .922.387 1.458.393.53 1.22.53.84 0 1.221-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.209-.524-.833 0-1.226.524t-.393 1.453M124.352 33.912h-.62v-2.286h-2.512v2.286h-.613v-4.899h.613v2.072h2.512v-2.072h.62z\"/\u003e\u003c/g\u003e\u003cpath fill=\"#c6c62c\" stroke=\"none\" d=\"M141.916 24.98q0 .649-.477 1.018-.47.363-1.268.363-.416 0-.768-.066-.345-.059-.577-.172v-.59q.244.113.607.203.369.089.762.089.548 0 .828-.214.279-.215.279-.578 0-.238-.107-.399-.101-.166-.351-.309t-.697-.298q-.625-.226-.946-.553-.316-.334-.316-.899 0-.393.197-.667.202-.28.553-.429.358-.155.816-.155.405 0 .738.078.34.071.613.196l-.196.53q-.25-.113-.548-.184-.297-.078-.625-.078-.458 0-.69.197-.233.196-.233.518 0 .244.102.41.107.167.339.298.232.125.631.28.429.155.726.339.298.179.453.435.155.25.155.637\" class=\"atom\"/\u003e\u003cpath stroke=\"none\" d=\"M155.828 16.22q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.565.756-.881t1.274-.316q.732 0 1.232.316.5.31.756.875.256.566.256 1.328m-3.863 0q0 .922.386 1.458.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524-.392.524-.392 1.453M135.01 10.641q0 .756-.256 1.328-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.245-.571-.245-1.333 0-.751.245-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875.256.565.256 1.327m-3.864 0q0 .923.387 1.459.393.53 1.221.53.839 0 1.22-.53.387-.536.387-1.459 0-.928-.387-1.452-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.452\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M150.25 37.038q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.245-.571-.245-1.333 0-.75.245-1.31.25-.565.756-.881.506-.315 1.274-.315.732 0 1.232.315.5.31.756.875.256.566.256 1.328m-3.864 0q0 .923.387 1.458.393.53 1.221.53.839 0 1.22-.53.387-.535.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.227.524t-.393 1.453M154.556 39.491h-.619v-2.286h-2.512v2.286h-.613v-4.9h.613v2.072h2.512v-2.072h.619z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m130.451 29.57 3.588-2.072M130.451 29.57l3.588-2.072\" class=\"hi\"/\u003e\u003cpath stroke=\"#c6c62c\" d=\"m137.628 25.426-3.589 2.072M142.261 27.116l1.88 3.256\" class=\"hi\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"m146.021 33.629-1.88-3.257\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Title":"Lidocaine sulfate","UNII":"EYR84TH492"}],"Salts":["carbonate","tosylate","bicarbonate","iminodiacetic acid","maleate","hydrochloride","sulfate"],"Scheduling":[{"gov":"Australia","ref":["3"],"schedule":"S5, S4, and S2 substance"},{"gov":"Canada","ref":[],"schedule":"prescription only substance"},{"gov":"United Kingdom","ref":[],"schedule":"GSL, P, and prescription only substance"},{"gov":"United States","ref":[],"schedule":"prescription only substance"}],"Solubility":"VERY SOL IN ALC; SOL IN CHLOROFORM; INSOL IN ETHER; WHITE CRYSTALLINE POWDER /LIDOCAINE HYDROCHLORIDE/","Stability/Shelf Life":"Commercially available solutions of lidocaine hydrochloride in 5% dextrose usually are stable for 18 months after the date of manufacture. Commercially available solutions of lidocaine hydrochloride in 5% dextrose may be provided in plastic containers.","StereoisomerData":[],"Stereoisomers":[],"Structure":"\u003csvg xmlns=\"http://www.w3.org/2000/svg\" preserveAspectRatio=\"none\" style=\"display:block\" viewBox=\"0 0 107.667 47.685\"\u003e\u003crect width=\"100%\" height=\"100%\" fill=\"#fff\"/\u003e\u003cdesc\u003eGenerated by the Chemistry Development Kit (http://github.com/cdk)\u003c/desc\u003e\u003cg fill=\"#3050f8\" stroke=\"#000\" stroke-linecap=\"round\" stroke-linejoin=\"round\" stroke-width=\".7\"\u003e\u003cpath fill=\"#fff\" stroke=\"none\" d=\"M0 0h108v48H0z\"/\u003e\u003cg class=\"mol\"\u003e\u003cpath d=\"m106.629 23.779-13.198-7.62M93.431 16.159l-10.045 5.799M80.232 27.628v11.391M80.232 39.019l13.199 7.62M77.079 21.958l-10.045-5.799M67.034 16.159l-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M55.055 23.075v12.022M52.617 23.075v12.022\"/\u003e\u003cpath stroke=\"#ff0d0d\" d=\"M55.055 35.097v-6.011M52.617 35.097v-6.011\" class=\"hi\"/\u003e\u003c/g\u003e\u003cpath d=\"m53.836 23.779-10.045-5.8M37.484 17.979l-10.044 5.8\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m27.444 39.027-.004-15.248M25.006 37.619l-.004-12.433\"/\u003e\u003c/g\u003e\u003cpath d=\"m27.444 39.027-13.198 7.62\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"m1.043 39.019 13.203 7.628M3.481 37.611l10.766 6.22\"/\u003e\u003c/g\u003e\u003cpath d=\"M1.043 39.019 1.038 23.77\" class=\"bond\"/\u003e\u003cg class=\"bond\"\u003e\u003cpath d=\"M14.236 16.15 1.038 23.77M14.236 18.966 3.477 25.178\"/\u003e\u003c/g\u003e\u003cpath d=\"M27.44 23.779 14.236 16.15M14.236 16.15 14.239.91M27.444 39.027l13.2 7.618\" class=\"bond\"/\u003e\u003cpath stroke=\"none\" d=\"M82.173 26.228h-.72l-2.62-4.066h-.029l.029.596q.024.357.024.732v2.738h-.565v-4.899h.714l2.608 4.054h.029l-.018-.327-.023-.477q-.006-.262-.006-.482v-2.768h.577z\" class=\"atom\"/\u003e\u003cpath fill=\"#ff0d0d\" stroke=\"none\" d=\"M56.095 39.016q0 .756-.256 1.327-.256.566-.756.881t-1.244.316q-.756 0-1.262-.316-.506-.315-.756-.887-.244-.571-.244-1.333 0-.75.244-1.31.25-.566.756-.881t1.274-.316q.732 0 1.232.316.5.309.756.875t.256 1.328m-3.863 0q0 .922.387 1.458.392.53 1.22.53.839 0 1.22-.53.387-.536.387-1.458 0-.929-.387-1.453-.381-.524-1.208-.524-.834 0-1.226.524-.393.524-.393 1.453\" class=\"atom\"/\u003e\u003cg stroke=\"none\" class=\"atom\"\u003e\u003cpath d=\"M42.578 18.608h-.72l-2.619-4.066h-.03l.03.596q.024.357.024.732v2.738h-.566v-4.899h.714l2.608 4.054h.03l-.018-.327-.024-.477q-.006-.262-.006-.482v-2.768h.577zM42.442 13.147h-.62v-2.286H39.31v2.286h-.613V8.248h.613v2.071h2.512V8.248h.62z\"/\u003e\u003c/g\u003e\u003cpath stroke=\"#3050f8\" d=\"m83.386 21.958 5.023-2.9M80.232 27.628v5.695M77.079 21.958l-5.023-2.9M43.791 17.979l5.022 2.9M43.791 17.979l5.022 2.9M37.484 17.979l-5.022 2.9M37.484 17.979l-5.022 2.9\" class=\"hi\"/\u003e\u003c/g\u003e\u003c/g\u003e\u003c/svg\u003e","Subjective Effects":null,"Therapeutic Uses":"Anesthetics, Local; Anti-Arrhythmia Agents; Voltage-Gated Sodium Channel Blockers","Title":"Lidocaine","Toxicity Data":"LD50: 459 (346-773) mg/kg (oral, non-fasted female rats)\nLD50: 214 (159-324) mg/kg (oral, fasted female rats)","Treatment":"The first step in the management of systemic toxic reactions consists of immediate attention to the establishment and maintenance of a patent airway and assisted or controlled ventilation with oxygen and a delivery system capable of permitting immediate positive airway pressure by mask. If convulsions occur, the objective of the treatment is to maintain ventilation and oxygenation and support the circulation. Oxygen must be given and ventilation assisted if necessary (mask and bag or tracheal intubation). Should convulsions not stop spontaneously after 15-20 seconds, an anticonvulsant should be given i.v. to facilitate adequate ventilation and oxygenation. Thiopental sodium 1-3 mg/kg i.v. is the first choice. Alternatively diazepam 0.1 mg/kg bw i.v. may be used, although its action will be slow. Prolonged convulsions may jeopardise the patient's ventilation and oxygenation. If so, injection of a muscle relaxant (e.g. succinylcholine 1 mg/kg bw) will facilitate ventilation, and oxygenation can be controlled. Early endotracheal intubation must be considered in such situations. If cardiovascular depression is evident (hypotension, bradycardia), ephedrine 5-10 mg i.v. should be given and may be repeated, if necessary, after 2-3 minutes. Should circulatory arrest occur, immediate cardiopulmonary resuscitation should be instituted. Continual oxygenation and ventilation and circulatory support as well as treatment of acidosis are of vital importance. (L1712)","UNII":"98PI200987","Wikidata":"Q216935","Wikipedia":"Lidocaine","XLogP":2.3}