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Dimethyltryptamine

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DMT, N,N-DMT
Dimethyltryptamine
Salts
[]
Dimethyltryptamine fumarate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Dimethyltryptamine hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
188.27 g/mol [1]
AppearanceCrystals ... also reported as plates from ethanol and light petroleum [1]
Melting point46 °C [1]
Boiling point60-80 °C [1]
DecompositionWhen heated to decomposition if emits toxic fumes of /nitrogen oxides/. [1]
SolubilityFreely soluble in dilute acetic and dilute mineral acids [1]
2.5 [1]
Structural Identifiers
[]
C12H16N2 [1]
2-(1H-indol-3-yl)-N,N-dimethylethanamine [1]
CN(C)CCC1=CNC2=CC=CC=C21 [1]
InChI=1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3 [1]
InChIKeyDMULVCHRPCFFGV-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-life* Alone: 5 – 19 min[4] * With monoamine oxidase inhibitor: 1 – 4 hours
Duration of action* Inhalation: ≤15 min * Intravenous: ≤30 min[5] * Intramuscular injection|Intramuscular: 30 – 60 min * Oral administration|Oral with monoamine oxidase inhibitor: 4 – 6 hours
Dosing[]
Insufflated
[]
Light≤ 62.5 mg(1x - 50%)
Common62.5 - 75 mg
Strong75 - 87.5 mg
Heavy87.5 - 95 mg
Extreme95 mg +(1x - 50%)
Oral
[]
Light≤ 65.1 mg(1x - 50%)
Common65.1 - 130.1 mg
Strong130.1 - 195 mg
Heavy195 - 234 mg
Extreme234 mg +(1x - 50%)
Vaporized
[]
Light≤ 21.9 mg(2x - 40%)
Common21.9 - 30 mg(1x - 20%)
Strong30 - 45 mg(1x - 20%)
Heavy45 - 48 mg
Extreme48 mg +(1x - 20%)
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Dimethyltryptamine (also known as N,N-Dimethyltryptamine, N,n-dimethyltryptamine, Dimethyltryptamine, 2-(3-Indolyl)ethyldimethylamine, 3-(2-Dimethylaminoethyl)indole, 1H-Indole-3-ethanamine, N,N-dimethyl-, N,N-Dimethyl-1H-indole-3-ethylamine, 2-(1H-Indol-3-yl)-N,N-dimethylethanamine, DEA No. 7435 or 3-[2-(dimethylamino)ethyl]indole) is a psychedelic substance of the tryptamine class.

Chemistry

Salts []

Dimethyltryptamine is typically found in the form of its fumarate and hydrochloride salts.

 []

Dimethyltryptamine is a achiral mixture.

Subjective effects []

x86pup / Dimethyltryptamine []
Routes:
  • Vaporized
magnus / Dimethyltryptamine []
Routes:
  • Vaporized
Notes:
  • smoked off foil; visuals present; breakthrough when combined with lsd and ketamine (although I don’t remember anything much)
0xea / Dimethyltryptamine []
Routes:
  • Vaporized (15 - 30mg)
    Onset: 15 s
    Comeup: 30 s
    Duration: 3 m
Active Effects:Notes:
  • ~15mg vaporized produced very light effects but made me leave with newfound meaning and motivation
  • ~20mg vaporized produced feelings of shooting through space while completely clear in my head, very clean beautiful visuals
  • ~25mg vaporized produced feelings of being torn out of my body and lost in space

Experience reports []

There are currently 25+ experience reports involving dimethyltryptamine on :

 []

  • Australia: Dimethyltryptamine is a S9 substance.
  • Canada: Dimethyltryptamine is a Schedule III substance.
  • United Kingdom: Dimethyltryptamine is a Class A substance.
  • United States: Dimethyltryptamine is a Schedule I under the "Controlled Substances Act (CSA)".
  • Germany: Dimethyltryptamine is a Anlage I substance.
  • Brazil: Dimethyltryptamine is a F2 substance.[3]
  • United Nations: Dimethyltryptamine is a Schedule I drug under the "Convention on Psychotropic Substances 1971".
  • European Union: Dimethyltryptamine is a Illegal substance.

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 6089, N,N-Dimethyltryptamine. Accessed May 4, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/6089

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Dimethyltryptamine. UNII: WUB601BHAA. Global Substance Registration System. Accessed May 4, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/WUB601BHAA

  3. Anvisa. RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. July 24, 2023. Accessed May 4, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451

  4. Vollebregt R, Storm AE, Lucassen PJ, Somers M. Psychedelic Experiences Elicited by Serotonergic Psychedelics; Molecular Mechanisms and Functional Connectivity Changes in /the Brain. Neurosci Biobehav Rev. December 1, 2025; 181()

  5. Barker SA. Administration of N,N-dimethyltryptamine (DMT) in psychedelic therapeutics and research and the study of endogenous DMT. Psychopharmacology (Berl). June 1, 2022; 239(6):1749–1763.