AnodyneWiki

Disable conformers
Collapse all
Light theme

Cocaine

Read
Coke
Cocaine
Salts
[]
Cocaine hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Cocaine borate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Cocaine hydrobromide
Generated by the Chemistry Development Kit (http://github.com/cdk)
Cocaine hydriodide
Generated by the Chemistry Development Kit (http://github.com/cdk)
Cocaine hemicitrate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Rotamer
[]
Conformer structure via 3Dmol.js
Enable javascript to view conformer structure via 3Dmol.js
Physical properties
[]
303.35 g/mol [1]
AppearanceColorless to white crystals or white powder [1]
Melting point98 °C [1]
Boiling point187 °C [1]
DecompositionWhen heated to decomposition it emits highly toxic fumes. [1]
SolubilityCrystals; MP 58-63 °C; freely sol in water or alcohol, slightly sol in ether. /Cocaine nitrate dihydrate/ [1]
2.3 [1]
Structural Identifiers
[]
C17H21NO4 [1]
methyl (1R,2R,3S,5S)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate [1]
CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)C3=CC=CC=C3)C(=O)OC [1]
InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1 [1]
InChIKeyZPUCINDJVBIVPJ-LJISPDSOSA-N [1]
Pharmacokinetics[]
Elimination half-life~1 hour[4]
Duration of action20 – 90 minutes
Dosing[]
Insufflated
[]
Light≤ 18.4 mg(281x - 27.7%)
Common18.4 - 25 mg(299x - 29.4%)
Strong25 - 33 mg(183x - 18%)
Heavy33 - 45 mg(160x - 15.7%)
Extreme45 mg +(93x - 9.2%)
Intravenous
[]
Light≤ 25 mg(33x - 66%)
Common25 mg
Strong25 - 35 mg(5x - 10%)
Heavy35 - 100.1 mg(5x - 10%)
Extreme100.1 mg +(7x - 14%)
Oral
[]
Light≤ 27.9 mg(3x - 42.9%)
Common27.9 - 30 mg(2x - 28.6%)
Strong30 - 35 mg
Heavy35 - 46 mg(1x - 14.3%)
Extreme46 mg +(1x - 14.3%)
Intrarectal
[]
Light≤ 26.7 mg(38x - 48.7%)
Common26.7 - 32.5 mg(1x - 1.3%)
Strong32.5 - 53.8 mg(19x - 24.4%)
Heavy53.8 - 75 mg(15x - 19.2%)
Extreme75 mg +(5x - 6.4%)
Vaporized
[]
Light≤ 29.2 mg(5x - 31.3%)
Common29.2 - 33 mg(4x - 25%)
Strong33 - 46.3 mg(3x - 18.8%)
Heavy46.3 - 50 mg(3x - 18.8%)
Extreme50 mg +(1x - 6.3%)
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Cocaine (also known as Benzoylmethylecgonine, Neurocaine, Kokain, Cocain, Cocaina, β-Cocain, Methyl Benzoylecgonine, cocainum, Eritroxilina or Erytroxylin) is a stimulant substance of the tropane class.

Chemistry

Salts []

Cocaine is typically found in the form of its hydrochloride, borate, hydrobromide, hydriodide and hemicitrate salts.

 []

Cocaine is a absolute mixture.

Pharmacology

In the () cocaine acts as a anesthetic (), anesthetics, local (), cocaine () and esters of benzoic acid ().[1]In the () cocaine acts In the () cocaine acts In the () cocaine acts

Subjective effects []

class / Stimulant
Mere / Cocaine []
emily / Cocaine []
Routes:
  • Insufflated (40mg)
michalina / Cocaine []
Effects:
  • decreased appetite
  • increased libido
  • extremely euphoria
  • extremely talkative
  • chatty
  • geeking
  • invicible
Notes:
  • 0,5g Cocaine tried in december 2025 with my former friend
0xea / Cocaine []
Routes:
  • Intravenous
    Onset: 15 s
    Duration: 10 - 15 m
  • Vaporized
Salts:
  • Freebase
  • Hydrochloride
  • Citrate
Source:
  • Cocaine: Warschauer
  • Cocaine: Drug taxi
Effects:Odor:
  • vaporized freebase fishy
Pilz / Cocaine []
Routes:
  • Insufflated (10 - 30mg)
  • Oral (5 - 10mg)
Effects:Notes:
alina / Cocaine []
Routes:
  • Insufflated (mg)
magnus / Cocaine []
Routes:
  • Insufflated
Salts:
  • Hydrochloride
Effects:Notes:
  • recreational
a1ko / Cocaine []
Routes:
  • Insufflated
x86pup / Cocaine []
Routes:
  • Insufflated
  • Intravenous

Experience reports

Reddit

There are currently 192 trip reports involving cocaine on : []

 []

  • Australia: Cocaine is a Schedule 8 substance.
  • Brazil: Cocaine is a F1 substance.
  • Canada: Cocaine is a Schedule I substance.
  • Germany: Cocaine is a Anlage III substance.
  • New Zealand: Cocaine is a Class A substance.
  • United Kingdom: Cocaine is a Class A substance.
  • United States: Cocaine is a Schedule I under the "Controlled Substances Act (CSA)".[3]
  • United Nations: Cocaine is a Schedule I and III narcotic under the "Single Convention on Narcotic Drugs 1961".

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 446220, Cocaine. Accessed August 24, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/446220

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Cocaine. UNII: I5Y540LHVR. Global Substance Registration System. Accessed August 24, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/I5Y540LHVR

  3. DEA / Drug Scheduling. Accessed August 24, 2026. https://www.dea.gov/druginfo/ds.shtml

  4. Cocaine: Uses, Interactions, Mechanism of Action. Accessed August 24, 2026. https://go.drugbank.com/drugs/DB00907#:~:text=Half%2Dlife-,1%20hour,-Clearance