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Cocaine

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Cocaine
Cocaine
Salts
[]
Cocaine hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Cocaine borate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Cocaine hydrobromide
Generated by the Chemistry Development Kit (http://github.com/cdk)
Cocaine hydriodide
Generated by the Chemistry Development Kit (http://github.com/cdk)
Cocaine hemicitrate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
303.35 g/mol [1]
AppearanceColorless to white crystals or white powder [1]
Melting point98 °C [1]
Boiling point187 °C [1]
DecompositionWhen heated to decomposition it emits highly toxic fumes. [1]
SolubilityCrystals; MP 58-63 °C; freely sol in water or alcohol, slightly sol in ether. /Cocaine nitrate dihydrate/ [1]
2.3 [1]
Structural Identifiers
[]
C17H21NO4 [1]
methyl (1R,2R,3S,5S)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate [1]
CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)C3=CC=CC=C3)C(=O)OC [1]
InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1 [1]
InChIKeyZPUCINDJVBIVPJ-LJISPDSOSA-N [1]
Pharmacokinetics[]
Duration of action20 - 90 minutes

Cocaine is a stimulant substance of the phenyltropane class.

Chemistry

Salts []

Cocaine is typically found in the form of its hydrochloride, borate, hydrobromide, hydriodide and hemicitrate salts.

 []

Cocaine is a absolute mixture.

Pharmacology

In the () cocaine acts

Metabolism

Subjective effects []

alina / Cocaine []
Routes:
  • Insufflated (mg)
x86pup / Cocaine []
Routes:
  • Insufflated
  • Intravenous
magnus / Cocaine []
Routes:
  • Insufflated
Salts:
  • Hydrochloride
Active Effects:Notes:
  • recreational
Pilz / Cocaine []
Routes:
  • Insufflated (10 - 30mg)
  • Oral (5 - 10mg)
Active Effects:
0xea / Cocaine []
Routes:
  • Intravenous
    Onset: 15 s
    Duration: 10 - 15 m
  • Vaporized
Salts:
  • Freebase
  • Hydrochloride
  • Citrate
Source:
  • Cocaine: Warschauer
  • Cocaine: Drug taxi
Active Effects:Notes:
  • occasional comfortable full body feeling; vaporized strong fishy smell and numbness inside mouth

Legal status []

  • Australia: Cocaine is a Schedule 8 substance.
  • Brazil: Cocaine is a F1 substance.
  • Canada: Cocaine is a Schedule I substance.
  • Germany: Cocaine is a Anlage III substance.
  • New Zealand: Cocaine is a Class A substance.
  • United Kingdom: Cocaine is a Class A substance.
  • United States: Cocaine is a Schedule I under the "Controlled Substances Act (CSA)".[3]
  • United Nations: Cocaine is a Schedule I and III narcotic under the "Single Convention on Narcotic Drugs 1961".

See also []

  • Substituted phenyltropanes
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 446220, Cocaine. Accessed December 15, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/446220

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Cocaine. UNII: I5Y540LHVR. Global Substance Registration System. Accessed December 15, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/I5Y540LHVR

    3. DEA / Drug Scheduling. Accessed December 15, 2025. https://www.dea.gov/druginfo/ds.shtml