Anodyne

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Clindamycin

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Clindamycin
Clindamycin
Salts
[]
Clindamycin hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Rotamer
[]
Conformer structure via 3Dmol.js
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Physical properties
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425.0 g/mol [1]
AppearanceYellow, amorphous solid [1]
Melting point141-143C [1]
DecompositionWhen heated to decomposition it emits toxic fumes of /chlorine, oxides of sulfur, and oxides of nitrogen/. [1]
SolubilityWater soluble [1]
2.2 [1]
Structural Identifiers
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C18H33ClN2O5S [1]
(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide [1]
CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl [1]
InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1 [1]
InChIKeyKDLRVYVGXIQJDK-AWPVFWJPSA-N [1]
Pharmacokinetics[]
Elimination half-life2 – 3 hour

Clindamycin (also known as Clindamycin, 18323-44-9, Chlolincocin, Clinimycin, Clindamicina, Clindamycine, 7-Chlorolincomycin, 7(S)-Chloro-7-deoxylincomycin, Clindamycinum or 7-Chloro-7-deoxylincomycin) is a antibiotic substance of the pyrrolidine class.

Chemistry

Salts []

Clindamycin is typically found in the form of its hydrochloride salt.

 []

Clindamycin is a absolute mixture.

Pharmacology

Metabolism

Subjective effects []

0xea / Clindamycin []
  • Routes:
    • Oral
  • Indication:
    • antibiotic wound course used for infected eyelid

Legal status []

  • Australia: Clindamycin is a S4 substance.
  • Canada: Clindamycin is a prescription only substance.[3]
  • United Kingdom: Clindamycin is a prescription only substance.
  • United States: Clindamycin is a prescription only substance.

See also []

  • Substituted pyrrolidines
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 446598, Clindamycin. Accessed February 10, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/446598

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Clindamycin. UNII: 3U02EL437C. Global Substance Registration System. Accessed February 10, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/3U02EL437C

    3. Product monograph brand safety updates. June 6, 2024. Accessed February 10, 2026. https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/drug-product-database/label-safety-assessment-update/product-monograph-brand-safety-updates.html