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Quetiapine

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Quetiapine
Quetiapine
Molecular structure via molpic based on CDK
Physical properties
[]
383.5 g/mol [1]
AppearanceSolid [1]
Melting point174-176 [1]
Boiling point556.5±60.0 [1]
Solubility49.4 [ug/mL] (The mean of the results at pH 7.4) [1]
2.1 [1]
Structural Identifiers
[]
C21H25N3O2S [1]
2-[2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethoxy]ethanol [1]
C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42 [1]
InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 [1]
InChIKeyURKOMYMAXPYINW-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-life7 hours (parent compound); 9 – 12 hours (active metabolite, norquetiapine)Truven Health Analytics, Inc. DrugPoint System (Internet) [cited 2013 Sep 18]. Greenwood Village, CO: Thomsen Healthcare; 2013.
Dosing[]
Oral
[]
Light≤ 25 mg(33x - 68.8%)
Common25 mg
Strong25 - 50 mg(9x - 18.8%)
Heavy50 - 115 mg(1x - 2.1%)
Extreme115 mg +(5x - 10.4%)
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Quetiapine (also known as quetiapina, Norsic, quetiapinum, 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol, Quetiapine extended release, NSC-758918, 2-(2-(4-Dibenzo(b,f)(1,4)thiazepin-11-yl-1-piperazinyl)ethoxy)ethanol, Ethanol, 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-, CHEBI:8707 or Dtxcid903546) is a substance of the 1-benzylpiperazine class.

Chemistry

 []

Quetiapine is a achiral mixture.

Pharmacology

In the () quetiapine acts as a antipsychotic (), diazepines, oxazepines, thiazepines and oxepine (), psycholeptic () and quetiapine ().[1]

Interactions []

induction / inhibition

Subjective effects []

magnus / Quetiapine []
Routes:
  • Oral
bonzi / Quetiapine []
Pilz / Quetiapine []
Routes:
  • Oral (10 - 50mg)
Salts:
  • Hemifumarate
Indication:Effects:Notes:
  • Helpful as a tripkiller
  • Very effective as a sleep aid; but has a hangover
0xea / Quetiapine []
Routes:
  • Oral
    Onset: 35 - 45 m
    Comeup: 1 - 3 h
    Duration: 6 - 8 h
  • Insufflated
  • Intravenous
    Onset: 15 s
    Comeup: 1 - 5 m
    Duration: ?
Salts:
  • Hemifumarate
Indication:Effects:Notes:
  • unsure about effects on allergy

Experience reports

Erowid

There are currently 26 experience reports involving quetiapine on : []

 []

  • Australia: Quetiapine is a S4 substance.[3]
  • Brazil: Quetiapine is a C1 substance.
  • Canada: Quetiapine is a prescription only substance.
  • New Zealand: Quetiapine is a Prescription only substance.
  • United Kingdom: Quetiapine is a prescription only substance.
  • United States: Quetiapine is a prescription only substance.

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 5002, quetiapine. Accessed May 17, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/5002

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Quetiapine. UNII: BGL0JSY5SI. Global Substance Registration System. Accessed May 17, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/BGL0JSY5SI

  3. Prescription medicines: registration of new generic medicines and biosimilar medicines, 2017. June 21, 2022. Accessed May 17, 2026. https://www.tga.gov.au/resources/publication/publications/prescription-medicines-registration-new-generic-medicines-and-biosimilar-medicines-2017