HWA 285, HWA-285 | |
---|---|
Molecular structure via molpic based on CDK |
Rotamer [] | |
---|---|
Physical properties [] | |
---|---|
Molecular mass | 306.36 g/mol [1] |
Predicted LogP | 0.7 [1] |
Structural Identifiers [] | |
---|---|
Molecular formula | C15H22N4O3 [1] |
IUPAC name | 3-methyl-1-(5-oxohexyl)-7-propylpurine-2,6-dione [1] |
SMILES | CCCN1C=NC2=C1C(=O)N(C(=O)N2C)CCCCC(=O)C [1] |
InChI | InChI=1S/C15H22N4O3/c1-4-8-18-10-16-13-12(18)14(21)19(15(22)17(13)3)9-6-5-7-11(2)20/h10H,4-9H2,1-3H3 [1] |
InChIKey | RBQOQRRFDPXAGN-UHFFFAOYSA-N [1] |
Toxicity [] | |
---|---|
LD50 | Mouse: - oral: 780 mg/kg - intraperitoneal: 346 mg/kg - subcutaneous: 450 mg/kg - intravenous: 107 mg/kg Rabbit: - oral: 405 mg/kg - intravenous: 89 mg/kg Rat: - oral: 940 mg/kg - intraperitoneal: 196 mg/kg - subcutaneous: 338 mg/kg - intravenous: 180 mg/kg |
Propentofylline
Propentofylline (also known as Propentophylline, HWA 285, HWA-285, Propentofyllinum, 3,7-Dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-1H-purine-2,6-dione, Propentofilina, 1H-Purine-2,6-dione, 3,7-dihydro-3-methyl-1-(5-oxohexyl)-7-propyl-, 1-(5'-oxohexyl)-3-methyl-7-propylxanthine, RefChem:869635 or N06BC02) is a
Chemistry
Stereochemistry []
Propentofylline is a achiral mixture
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 4938, Propentofylline. Accessed September 15, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/4938
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Propentofylline. UNII: 5RTA398U4H. Global Substance Registration System. Accessed September 15, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/5RTA398U4H