Anodyne

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Oxazepam
Oxazepam
Esters
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Oxazepam acetate
Oxazepam acetate
Molecular structure via molpic based on CDK
[]
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Physical properties
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286.71 g/mol [1]
AppearanceCrystals from alcohol [1]
OdorPRACTICALLY ODORLESS [1]
TasteBITTER [1]
Melting point401 to 403 °F (NTP, 1992) [1]
Solubilityless than 1 mg/mL at 66 °F (NTP, 1992) [1]
2.2 [1]
Structural Identifiers
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C15H11ClN2O2 [1]
7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one [1]
C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O [1]
InChI=1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19) [1]
InChIKeyADIMAYPTOBDMTL-UHFFFAOYSA-N [1]
Dosing
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Elimination half-life6–9 hours[https://www.has-sante.fr/upload/docs/application/pdf/2011-11/mama_troubles_comportement_encadre_1_anxiolitiques.pdf Encadré 1. Anxiolytiques à demi-vie courte (< 20 heures) et sans métabolite actif par ordre alphabétique de DCI][4][5]
Duration of action6 - 12 hours

Oxazepam

Oxazepam (also known as Droxacepam, Zaxopam, Ansioxacepam, Durazepam, Noctazepam, Psiquiwas, Quilibrex, Anxiolit, Aplakil or Astress) is a substance of the benzodiazepine class.

Chemistry

Salts and Esters []

Oxazepam is typically found in the form of its potassium and hydrochloride salts

or its ester.

 []

(RS)-Oxazepam is a racemic mixture of the optical stereoisomers

Experience reports []

There are currently 1 experience reports involving oxazepam on OpenErowid:

Legal status []

  • Australia: Oxazepam is a S4 substance.
  • Brazil: Oxazepam is a B1 substance.[3]
  • Canada: Oxazepam is a Schedule IV substance.
  • Germany: Oxazepam is a prescription only/Anlage III substance.
  • United States: Oxazepam is a Schedule I under the "Controlled Substances Act (CSA)".

See also []

  • Substituted benzodiazepines (benzos)
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 4616, Oxazepam. Accessed June 25, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/4616

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Oxazepam. UNII: 6GOW6DWN2A. Global Substance Registration System. Accessed June 25, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/6GOW6DWN2A

    3. Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed June 25, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992

    4. Sonne J, Loft S, Døssing M, Vollmer-Larsen A, Olesen KL, Victor M, Andreasen F, Andreasen PB. Bioavailability and pharmacokinetics of oxazepam. European Journal of Clinical Pharmacology. 1988; 35(4):385–389.

    5. Sonne J, Boesgaard S, Poulsen HE, Loft S, Hansen JM, Døssing M, Andreasen F. Pharmacokinetics and pharmacodynamics of oxazepam and metabolism of paracetamol in severe hypothyroidism. British Journal of Clinical Pharmacology. November 1, 1990; 30(5):737–742.