Anodyne| Oxazepam | |
|---|---|
 | |
| Esters [] | |
|---|---|
| Oxazepam acetate | |
|
| Molecular structure via molpic based on CDK |
| Conformer [] | |
|---|---|
| Conformer structure via JSmol | |
| Physical properties [] | |
|---|---|
| Molecular mass | 286.71 g/mol [1] |
| Appearance | Crystals from alcohol [1] |
| Odor | PRACTICALLY ODORLESS [1] |
| Taste | BITTER [1] |
| Melting point | 401 to 403 °F (NTP, 1992) [1] |
| Solubility | less than 1 mg/mL at 66 °F (NTP, 1992) [1] |
| Predicted LogP | 2.2 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C15H11ClN2O2 [1] |
| IUPAC name | 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one [1] |
| SMILES | C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O [1] |
| InChI | InChI=1S/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19) [1] |
| InChIKey | ADIMAYPTOBDMTL-UHFFFAOYSA-N [1] |
| Dosing [] | |
|---|---|
| Elimination half-life | 6–9 hours[https://www.has-sante.fr/upload/docs/application/pdf/2011-11/mama_troubles_comportement_encadre_1_anxiolitiques.pdf Encadré 1. Anxiolytiques à demi-vie courte (< 20 heures) et sans métabolite actif par ordre alphabétique de DCI][4][5] |
| Duration of action | 6 - 12 hours |
Oxazepam
Oxazepam (also known as Droxacepam, Zaxopam, Ansioxacepam, Durazepam, Noctazepam, Psiquiwas, Quilibrex, Anxiolit, Aplakil or Astress) is a
Chemistry
Salts and Esters []
Stereochemistry []
(RS)-Oxazepam is a racemic mixture of the optical stereoisomers
Experience reports []
There are currently 1 experience reports involving oxazepam on OpenErowid:
Legal status
- Australia: Oxazepam is a S4 substance.
- Brazil: Oxazepam is a B1 substance.[3]
- Canada: Oxazepam is a Schedule IV substance.
- Germany: Oxazepam is a prescription only/Anlage III substance.
- United States: Oxazepam is a Schedule I under the "Controlled Substances Act (CSA)".
See also []
External links []
- Oxazepam (Wikipedia)
- Oxazepam (Wikidata)
- Oxazepam (DrugBank)
- Oxazepam / (+)-Oxazepam / (-)-Oxazepam (PubChem)
- Oxazepam / (+)-Oxazepam / (-)-Oxazepam (ChEMBL)
- Oxazepam (ChEBI)
- Oxazepam / (+)-Oxazepam / (-)-Oxazepam (Common Chemistry)
- Oxazepam (HMDB)
- Oxazepam (KEGG)
- Oxazepam / (+)-Oxazepam / (-)-Oxazepam (UNII)
- Oxazepam (EPA DSSTox)
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 4616, Oxazepam. Accessed June 25, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/4616
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Oxazepam. UNII: 6GOW6DWN2A. Global Substance Registration System. Accessed June 25, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/6GOW6DWN2A
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed June 25, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992
Sonne J, Loft S, Døssing M, Vollmer-Larsen A, Olesen KL, Victor M, Andreasen F, Andreasen PB. Bioavailability and pharmacokinetics of oxazepam. European Journal of Clinical Pharmacology. 1988; 35(4):385–389.
Sonne J, Boesgaard S, Poulsen HE, Loft S, Hansen JM, Døssing M, Andreasen F. Pharmacokinetics and pharmacodynamics of oxazepam and metabolism of paracetamol in severe hypothyroidism. British Journal of Clinical Pharmacology. November 1, 1990; 30(5):737–742.