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Lisdexamphetamine

Vyvanse
Lisdexamphetamine
Molecular structure via molpic based on CDK
Rotamer
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Conformer structure via 3Dmol.js
Enable javascript to view conformer structure via 3Dmol.js
Physical properties
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263.38 g/mol [1]
AppearanceGolden-colored solid from methanol [1]
Melting point191-193 [1]
SolubilityWhite to off-white powder. MP 120-122 °C. Solubility in water: 792 mg/mL /Lisdexamfetamine dimethanesulfonate/ [1]
1.2 [1]
Structural Identifiers
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C15H25N3[1]
(2S)-2,6-diamino-N-[(2S)-1-phenylpropan-2-yl]hexanamide [1]
C[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)N [1]
InChI=1S/C15H25N3O/c1-12(11-13-7-3-2-4-8-13)18-15(19)14(17)9-5-6-10-16/h2-4,7-8,12,14H,5-6,9-11,16-17H2,1H3,(H,18,19)/t12-,14-/m0/s1 [1]
InChIKeyVOBHXZCDAVEXEY-JSGCOSHPSA-N [1]

Lisdexamphetamine (also known as Lisdexamfetamine, lysine-d-amphetamine, lisdexanfetamina, lysine-dextroamphetamine, (2S)-2,6-Diamino-N-((1S)-1-methyl-2-phenylethyl)hexanamide, (2S)-2,6-Diamino-N-[(1S)-1-methyl-2-phenylethyl]hexanamide, (2S)-2,6-diamino-N-((2S)-1-phenylpropan-2-yl)hexanamide, lisdexamfetaminum, (2S)-2,6-diamino-N-((2S)-1-phenylpropan-2-yl)hexanimidic acid or (2S)-2,6-diamino-N-[(2S)-1-phenylpropan-2-yl]hexanimidic acid) is a codrug, prodrug and stimulant substance of the amphetamine class.

Chemistry

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Lisdexamphetamine is a achiral mixture.

Pharmacology

In the () lisdexamphetamine acts

Metabolism

Lisdexamphetamine acts as a for:

Metabolic pathways []
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Lisdexamphetamine
Lisdexamphetamine


Subjective effects []

alina / Lisdexamphetamine []
Routes:
  • Oral (10 - 60mg)
bonzi / Lisdexamphetamine []
Routes:
  • Oral (20 - 70mg)
emily / Lisdexamphetamine []
Routes:
  • Oral (10 - 80mg)
magnus / Lisdexamphetamine []
Routes:
  • Oral (70mg)
Salts:
  • Dimesylate
Active Effects:Notes:
Pilz / Lisdexamphetamine []
Routes:
  • Oral (5 - 60mg)
Salts:
  • Dimesilat
Indication:
  • Attention-Deficit/Hyperactivity Disorder
Active Effects:Notes:
  • Best ADHD-Medication ive tried
0xea / Lisdexamphetamine []
Routes:
  • Oral (30 - 150mg)
    Onset: 1.5 - 2 h
    Duration: 7 - 13 h
  • Intravenous (50 - 150mg)
    Onset: 1 h
    Duration: ?
Salts:
  • Dimesylate
Source:
  • Elvanse Lisdexamfetamine dimesylate
Indication:
  • executive dysfunction
Active Effects:

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 11597698, Lisdexamphetamine. Accessed July 22, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/11597698