Anodyne

E2
Estradiol
Esters
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Estradiol acetate
Estradiol acetate
Estradiol benzoate
Estradiol benzoate
Estradiol valerate
Estradiol valerate
Estradiol cypionate
Estradiol cypionate
Estradiol enantate
Estradiol enantate
Estradiol undecylate
Estradiol undecylate
Estradiol diundecylate
Estradiol diundecylate
Estradiol propionate
Estradiol propionate
Estradiol dipropionate
Estradiol dipropionate
Molecular structure via molpic based on CDK
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Physical properties
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272.4 g/mol [1]
AppearanceWhite crystalline powder. Prisms from 80% alcohol [1]
OdorOdorless [1]
Melting point178.5 °C [1]
Boiling point445.9±45.0 [1]
DecompositionWhen heated to decomposition it emits acrid smoke and irritating fumes. [1]
SolubilityVery soluble in acetone, ethanol, dioxane [1]
[1]
Structural Identifiers
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C18H24O2 [1]
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol [1]
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O [1]
InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1 [1]
InChIKeyVOXZDWNPVJITMN-ZBRFXRBCSA-N [1]

Estradiol

Estradiol (also known as Oestradiol, progynon, Diogynets, Aquadiol, Climara, Diogyn, Vagifem, Dimenformon, Estraderm or Estraldine)

Chemistry

Salts and Esters []

Estradiol is typically found in the form of its sodium and hemihydrate salts

or its acetate, benzoate, valerate, cypionate, enantate, undecylate, diundecylate, propionate and dipropionate esters.

 []

Estradiol is a absolute mixture

Anodyne Usernotes
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0xea / Estradiol[hemihydrate] via life saving hormone; caused figure changes, breast growth, body hair reduction, skin smoothing and emotional enhancements

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 5757, Estradiol. Accessed July 5, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/5757

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Estradiol. UNII: 4TI98Z838E. Global Substance Registration System. Accessed July 5, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/4TI98Z838E