Anodyne

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Doxycycline
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
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Physical properties
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444.4 g/mol [1]
-0.7 [1]
Structural Identifiers
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C22H24N2O8 [1]
(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide [1]
C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O [1]
InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25-27,30,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1 [1]
InChIKeySGKRLCUYIXIAHR-AKNGSSGZSA-N [1]
Dosing
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Elimination half-life10 – 22 hours
Toxicity
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Human - female:
- oral: 68 mg/kg/24D-I
Rat:
- oral: >2 gm/kg
- intraperitoneal: 378 mg/kg
- intravenous: 228 mg/kg
Mouse:
- oral: 1870 mg/kg
- intraperitoneal: 410 mg/kg
- intravenous: 241 mg/kg
Dog:
- oral: >500 mg/kg
- intravenous: >100 mg/kg

Doxycycline

Doxycycline (also known as 4-(Dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-3,4,4a,5,5a,6,12,12a-octahydrotetracene-2-carboximidic acid, 7164-70-7, RefChem:1070088, Doxytetracycline, Vibramycin, Doxiciclina, Doxycyclinum, Monodox, Doxycycline anhydrous or 6-Deoxytetracycline) is a antibiotic substance of the aniline class.

Chemistry

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Doxycycline is a absolute mixture

Legal status []

  • Australia: Doxycycline is a S4 substance.
  • United Kingdom: Doxycycline is a prescription only substance.
  • United States: Doxycycline is a prescription only substance.

See also []

  • Substituted anilines
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 54671203, Doxycycline. Accessed September 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/54671203

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Doxycycline. UNII: 334895S862. Global Substance Registration System. Accessed September 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/334895S862