| CP, CPM | |
|---|---|
| Salts [] | |
|---|---|
| Chlorphenamine hydrochloride | |
| Chlorphenamine maleate | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 274.79 g/mol [1] |
| Appearance | OILY LIQUID [1] |
| Melting point | 130 - 135 °C [1] |
| Boiling point | 142 °C [1] |
| Solubility | UV max absorption (water): 261 nm (E=5760), Solubility in mg/ml at 25 °C: Ethanol 330; chloroform 240; water 160; methanol 130; pH of a 2% aqueous solution about 5 /Maleate/ [1] |
| Predicted LogP | 3.4 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C16H19ClN2 [1] |
| IUPAC name | 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine [1] |
| SMILES | CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 [1] |
| InChI | InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3 [1] |
| InChIKey | SOYKEARSMXGVTM-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 13.9 – 43.4 hours |
Chlorphenamine
Chlorphenamine (also known as Chlorpheniramine, chlorpheniramine, Chlorphenamine, 132-22-9, Chlorophenylpyridamine, Haynon, Clorfeniramina, Allergican, Allergisan or Clorfenamina) is a
Chemistry
Salts []
Chlorphenamine is typically found in the form of its hydrochloride and maleate salts.
Stereochemistry []
Chlorphenamine is a racemic mixture of the enantiomers
Legal status []
- Australia: Chlorphenamine is a S3 substance.
- United Kingdom: Chlorphenamine is a P substance.
- United States: Chlorphenamine is a OTC substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 2725, Chlorpheniramine. Accessed January 13, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/2725
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Chlorphenamine. UNII: 3U6IO1965U. Global Substance Registration System. Accessed January 13, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/3U6IO1965U