Anodyne

6-MAM
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
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327.4 g/mol [1]
1.3 [1]
Structural Identifiers
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C19H21NO4 [1]
[(4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl] acetate [1]
CC(=O)O[C@H]1C=C[C@H]2[C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)O)CCN3C [1]
InChI=1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1 [1]
InChIKeyJJGYGPZNTOPXGV-SSTWWWIQSA-N [1]
Dosing
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Elimination half-life0.6 hours
Toxicity
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Mouse:
- intravenous: 59 mg/kg
- intracrebral: 147 mg/kg

6-Monoacetylmorphine

6-Monoacetylmorphine (also known as 6-Acetylmorphine, 6-O-Monoacetylmorphine, 6-O-Acetylmorphine, 6-MAM, morphine-6-acetate, 6-MAM cpd, 6-(0-acetyl)morphine, RefChem:540029, ((4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro(3,2-e)isoquinoline-7-yl) acetate or Monoacetylmorphine) is a opioid substance of the morphinan class.

Chemistry

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6-Monoacetylmorphine is a absolute mixture

Subjective effects []

Anodyne Usernotes
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0xea / 6-Monoacetylmorphine[citrate] via Intravenousobtained by letting diacetylmorphine sit in a low pH solution for several weeks; quite potent; relaxing to the point of inducing sleep; warm; minor pain reduction; helps deal with siginificant emotional pain; weird dream like states which feel fully concious; encourages sexuality

Legal status []

  • Australia: 6-Monoacetylmorphine is a S9 substance.
  • United Kingdom: 6-Monoacetylmorphine is a Class A substance.

See also []

External links []

References []

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 5462507, 6-Monoacetylmorphine. Accessed September 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/5462507

  2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 6-Monoacetylmorphine. UNII: M5E47P1ZCH. Global Substance Registration System. Accessed September 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/M5E47P1ZCH