AnodyneWiki

3-Chloromethylphenidate

3-Cl-MPH

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	267.75 g/mol ^[1]
Predicted LogP	0.8 ^[1]

Structural Identifiers []
Molecular formula	C₁₄H₁₈ClNO₂ ^[1]
IUPAC name	methyl 2-(3-chlorophenyl)-2-piperidin-2-ylacetate ^[1]
SMILES	COC(=O)C(C1CCCCN1)C2=CC(=CC=C2)Cl ^[1]
InChI	InChI=1S/C14H18ClNO2/c1-18-14(17)13(12-7-2-3-8-16-12)10-5-4-6-11(15)9-10/h4-6,9,12-13,16H,2-3,7-8H2,1H3 ^[1]
InChIKey	QFEWAERCGCLJNU-UHFFFAOYSA-N ^[1]

3-Chloromethylphenidate (also known as Schembl2135899) is a stimulant substance of the phenidate class.

Chemistry

Stereochemistry []

3-Chloromethylphenidate is a racemic mixture of the diastereomers.

Stereoisomerism
(4S,5S)-3-Chloromethylphenidate (4R,5S)-3-Chloromethylphenidate (4S,5R)-3-Chloromethylphenidate (4R,5R)-3-Chloromethylphenidate
Stereoisomer enumberation with rdkit

Subjective effects []

class / Stimulant

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

See also []

External links []

3-Chloromethylphenidate (PubChem)

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 67290264, Schembl2135899. Accessed May 8, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/67290264