Anodyne

DOPA, L-DOPA

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	197.19 g/mol ^[1]
Appearance	Colorless to white crystals or crystalline powder; needles from water ^[1]
Odor	Odorless ^[1]
Taste	Tasteless ^[1]
Melting point	284-286 °C ^[1]
Decomposition	When heated to decomposition it emits toxic fumes of /nitrogen oxides/. ^[1]
Solubility	5mM ^[1]
Predicted LogP	-2.7 ^[1]

Structural Identifiers []
Molecular formula	C₉H₁₁NO₄ ^[1]
IUPAC name	(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid ^[1]
SMILES	C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O ^[1]
InChI	InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1 ^[1]
InChIKey	WTDRDQBEARUVNC-LURJTMIESA-N ^[1]

Pharmacokinetics[]
Elimination half-life	0.75 – 1.5 hours

3,4-Dihydroxyphenylalanine

3,4-Dihydroxyphenylalanine is a substance of the amino acid and catecholamine class.

Chemistry

Stereochemistry []

3,4-Dihydroxyphenylalanine is a absolute mixture

Anodyne Usernotes []
0xea / 3,4-Dihydroxyphenylalanine via Oral	subjective locomotor-activity increase; subjective mood-improvement

Legal status []

Australia: 3,4-Dihydroxyphenylalanine is a S4 substance.
United Kingdom: 3,4-Dihydroxyphenylalanine is a prescription only substance.
United States: 3,4-Dihydroxyphenylalanine is a prescription only substance.
European Union: 3,4-Dihydroxyphenylalanine is a prescription only substance.

See also []

Substituted amino acids

Substituted catecholamines

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 6047, Levodopa. Accessed November 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/6047
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. 3,4-Dihydroxyphenylalanine. UNII: 46627O600J. Global Substance Registration System. Accessed November 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/46627O600J