Anodyne

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Zopiclone
Generated by the Chemistry Development Kit (http://github.com/cdk)
Salts
[]
Zopiclone hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
388.8 g/mol [1]
Melting point178 °C [1]
Solubility>58.3 [ug/mL] (The mean of the results at pH 7.4) [1]
0.5 [1]
Structural Identifiers
[]
C17H17ClN6O3 [1]
[6-(5-chloro-2-pyridinyl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate [1]
CN1CCN(CC1)C(=O)OC2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)Cl [1]
InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3 [1]
InChIKeyGBBSUAFBMRNDJC-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-life~5 hours (3.5 – 6.5 hours) ~7 – 9 hours for 65+ years old
Toxicity
[]
Rat:
- oral: 827 mg/kg
- intraperitoneal: 771 mg/kg
- subcutaneous: 540 mg/kg
- intravenous: 280 mg/kg
- intramuscular: 295 mg/kg
Mouse:
- oral: 2174 mg/kg
- intraperitoneal: 1325 mg/kg
- subcutaneous: 888 mg/kg
- intravenous: 321 mg/kg
- intramuscular: 541 mg/kg
Dosing[]
Sublingual
[]
Light≤ 6.8 mg
Common6.8 - 8.8 mg
Strong8.8 - 10 mg
Heavy10 - 14.7 mg
Extreme14.7 mg +
Oral
[]
Light≤ 13.2 mg
Common13.2 - 20 mg
Strong20 - 22.5 mg
Heavy22.5 - 30 mg
Extreme30 mg +
Statistically derived dosages via DBI-IGS
We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly.

Zopiclone

Zopiclone (also known as Imovane, Zimovane, Amoban, Zopiclona, Zopiclonum, Ximovan, RP-27267, RP 27267, [6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate or Zimovane LS) is a substance of the racetam class.

Chemistry

Salts []

Zopiclone is typically found in the form of its hydrochloride salt.

 []

Zopiclone is a racemic mixture of the

Stereoisomers
(R)-ZopicloneGenerated by the Chemistry Development Kit (http://github.com/cdk)
(S)-ZopicloneGenerated by the Chemistry Development Kit (http://github.com/cdk)
Anodyne Usernotes
[]
magnus / Zopiclone via Oral
    -

Legal status []

  • Australia: Zopiclone is a S4 substance.
  • Brazil: Zopiclone is a B1 substance.[3]
  • Canada: Zopiclone is a prescription only substance.
  • United Kingdom: Zopiclone is a Class C substance.
  • New Zealand: Zopiclone is a Class C substance.
  • United States: Zopiclone is a Schedule I under the "Controlled Substances Act (CSA)".

See also []

  • Substituted racetams
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 5735, Zopiclone. Accessed October 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/5735

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Zopiclone. UNII: 03A5ORL08Q. Global Substance Registration System. Accessed October 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/03A5ORL08Q

    3. Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed October 14, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992