Anodyne

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Temgicoluril
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
198.22 g/mol [1]
-0.9 [1]
Structural Identifiers
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C8H14N4O2 [1]
1,3,4,6-tetramethyl-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione [1]
CN1C2C(N(C1=O)C)N(C(=O)N2C)C [1]
InChI=1S/C8H14N4O2/c1-9-5-6(11(3)7(9)13)12(4)8(14)10(5)2/h5-6H,1-4H3 [1]
InChIKeyXIUUSFJTJXFNGH-UHFFFAOYSA-N [1]
Pharmacokinetics[]
Elimination half-life3 hours{-{cite patent | country = US | number = 20110070305 | inventor = Schwarz J, Weisspapir M | title = Sustained release pharmaceutical composition containing mebicar|url=https://www.google.com/patents/US20110070305 | assign1 = Alpharx Inc. | pubdate = 2011 – 03-24 }-}
Toxicity
[]
Rat:
- intraperitoneal: 3450 mg/kg
Mouse:
- intraperitoneal: 3800 mg/kg

Temgicoluril

Temgicoluril (also known as Mebicar, mebikar, Tetramethylglycoluril, Tetrahydro-1,3,4,6-tetramethylimidazo(4,5-d)imidazole-2,5(1H,3H)-dione, imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetramethyl-, Glycoluril, 1,3,4,6-tetramethyl-, 2,4,6,8-tetramethyl-2,4,6,8-tetraazabicyclo-(3.3.0)-octan-3,7-dione, Imidazo(4,5-d)imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetramethyl-, RefChem:810813 or (3as,6as)-1,3,4,6-tetramethyl-octahydro-(1,3)diazolo(4,5-d)imidazole-2,5-dione) is a substance of the cycloalkylamine class.

Chemistry

 []

Temgicoluril is a achiral mixture

Anodyne Usernotes
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0xea / Temgicoluril via Oral at 500mg oral

Legal status []

  • United States: Temgicoluril is a Unscheduled; not FDA approved substance.

See also []

  • Substituted cycloalkylamines
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 122282, Temgicoluril. Accessed October 5, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/122282

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Temgicoluril. UNII: 55FE6NPG89. Global Substance Registration System. Accessed October 5, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/55FE6NPG89