Naloxone

Molecular structure via molpic based on CDK

Conformer []
Conformer structure via JSmol

Physical properties []
Molecular mass	327.4 g/mol [1]
Appearance	Crystals from ethyl acetate [1]
Melting point	178 °C [1]
Decomposition	When heated to decomposition it emits toxic fumes of /nitrogen oxides/. [1]
Solubility	Soluble [1]
Predicted LogP	2.1 [1]

Structural Identifiers []
Molecular formula	C19H21NO4 [1]
IUPAC name	(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one [1]
SMILES	C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O [1]
InChI	InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 [1]
InChIKey	UZHSEJADLWPNLE-GRGSLBFTSA-N [1]

Sublingual []
Threshold	0.125 - 0.25 mg
Light	0.25 - 1 mg
Common	1 - 1.5 mg
Strong	1.5 - 2 mg
Heavy	2 - 3 mg

Statistically derived dosages by Sernyl

Naloxone

Naloxone (also known as l-Naloxone, n-Allylnoroxymorphone, (-)-Naloxone, Narcan, Naloxona, EN 1530 base, Naloxonum, Nalossone, N-Allyl-noroxymorphone or DBL Naloxone) is a substance of the morphinan class.

Chemistry