Anodyne

Diclofenac
Diclofenac
Salts
[]
Sodium diclofenac
Sodium diclofenac
Diclofenac potassium
Diclofenac potassium
Molecular structure via molpic
Conformer structure via 3Dmol.js
Molecular formulaC14H11Cl2NO2
Molecular mass296.1 g/mol
AppearanceCrystals from ether-petroleum ether
Predicted LogP4.4
Melting point283-285 °C
SolubilityIn water, 2.37 mg/L at 25 °C
Chiralityachiral
Identifiers
[]
IUPAC name2-[2-(2,6-dichloroanilino)phenyl]acetic acid
SMILESC1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl
InChIInChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
InChIKeyDCOPUUMXTXDBNB-UHFFFAOYSA-N
Dosing
Elimination half-life1.2–2 h (35% of the drug enters enterohepatic recirculation)

Diclofenac

Diclofenac (also known as Diclofenac acid, dichlofenac, Diclofenaco, Diclophenac, Diclofenacum, ProSorb-D, Zorovolex, Zorvolex, Diclofenamic acid or Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-) is a nonsteroidal anti-inflammatory drug substance of the gabapentinoid class.

Chemistry

Diclofenac is typically found in the form of its sodium and potassium salts.

Stereochemistry

Diclofenac is a achiral mixture

See also