Codeine

Salts []
Codeine hydrochloride

Codeine hydrobromide

Codeine phosphate

Codeine sulfate

Molecular structure via molpic

Conformer structure via 3Dmol.js
Molecular formula	C₁₈H₂₁NO₃
Molecular mass	299.4 g/mol
Density	1.32 at 68 °F (NTP, 1992) - Denser than water; will sink g/cm³
Appearance	Orthorhombic crystals from water, dilute alcohol, ether
Predicted LogP	1.1
Melting point	309 to 313 °F (after drying at 176 °F) (NTP, 1992)
Boiling point	482 °
Decomposition	When heated to decomposition it emits toxic fumes of /nitrogen oxides/.
Solubility	less than 1 mg/mL at 70 °F (NTP, 1992)
Chirality	absolute

Identifiers []
IUPAC name	(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
SMILES	CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](C=C4)O
InChI	InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1
InChIKey	OROGSEYTTFOCAN-DNJOTXNNSA-N

Dosing

Insufflated []
Threshold	0.66 - 0.754 tablets
Light	0.754 - 1.5 tablets
Common	1.5 - 12.5 tablets
Strong	12.5 - 30 tablets
Heavy	30 - 51.99999999999999 tablets

Oral []
Threshold	0.5 - 4 mg
Light	4 - 24 mg
Common	24 - 60 mg
Strong	60 - 145.5 mg
Heavy	145.5 - 220 mg

Statistically derived dosages by Sernyl

Codeine

Codeine (also known as Methylmorphine, Codeine anhydrous, Codicept, Coducept, l-Codeine, Morphine monomethyl ether, O3-Methylmorphine, (-)-Codeine, Morphine 3-methyl ether or codeinum) is a substance of the morphinan class.

Chemistry

Codeine is typically found in the form of its hydrochloride, hydrobromide, phosphate and sulfate salts.

Stereochemistry

Codeine is a absolute mixture

Anodyne

Codeine

Chemistry

Stereochemistry

See also

External links