Anodyne

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Bupropion
Generated by the Chemistry Development Kit (http://github.com/cdk)
Salts
[]
%!s() hydrobromide
Generated by the Chemistry Development Kit (http://github.com/cdk)
%!s() hydrochloride
Generated by the Chemistry Development Kit (http://github.com/cdk)
%!s() maleate
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
Physical properties
[]
239.74 g/mol [1]
AppearancePale yellow oil [1]
Melting point233-234 °C [1]
Boiling point52 °C [1]
SolubilityVery hygroscopic and susceptible to decomposition [1]
3.2 [1]
Structural Identifiers
[]
C13H18ClNO [1]
2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one [1]
CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C [1]
InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3 [1]
InChIKeySNPPWIUOZRMYNY-UHFFFAOYSA-N [1]

Bupropion

Bupropion (also known as Amfebutamone, Amfebutamon, amfebutamonum, Amfebutamona, Elontril, Bupropion slow release, bupropione, Bupropion extended release, α-(tert-butylamino)-m-chloropropiophenone or 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone) is a stimulant substance of the cathinone class.

Chemistry

Salts []

Bupropion is typically found in the form of its hydrobromide, hydrochloride and maleate salts.

 []

Bupropion is a racemic mixture of the

Stereoisomers
(R)-BupropionGenerated by the Chemistry Development Kit (http://github.com/cdk)
(S)-BupropionGenerated by the Chemistry Development Kit (http://github.com/cdk)

Pharmacology

Bupropion acts as a for:

Active metabolites
 []
Hydroxybupropion Generated by the Chemistry Development Kit (http://github.com/cdk)
Threohydrobupropion Generated by the Chemistry Development Kit (http://github.com/cdk)
Erythrohydrobupropion Generated by the Chemistry Development Kit (http://github.com/cdk)

Subjective effects []

Anodyne Usernotes
[]
0xea / Bupropion[hydrochloride] via Oral and Intravenous at 150mg oral and 300mg intravenous

See also []

  • Substituted cathinones
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 444, Bupropion. Accessed July 19, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/444

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Bupropion. UNII: 01ZG3TPX31. Global Substance Registration System. Accessed July 19, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/01ZG3TPX31