Aripiprazole
| Aripiprazole | |
|---|---|
 |
| Salts [] | |
|---|---|
| Aripiprazole monohydrate | |
| Molecular structure via molpic based on CDK |
| Rotamer [] | |
|---|---|
| Conformer structure via 3Dmol.js |
| Physical properties [] | |
|---|---|
| Molecular mass | 448.4 g/mol [1] |
| Appearance | Colorless, flake crystals from ethanol [1] |
| Melting point | 137-140 [1] |
| Boiling point | 139.0-139.5 °C [1] |
| Solubility | 0.00001% [1] |
| Predicted LogP | 4.6 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C23H27Cl2N3O2 [1] |
| IUPAC name | 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one [1] |
| SMILES | C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl [1] |
| InChI | InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) [1] |
| InChIKey | CEUORZQYGODEFX-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 75 hours (active metabolite is 94 hours) |
Aripiprazole (also known as Abilify, Abilitat, OPC-14597, Abilify Discmelt, aripiprazol, Discmelt, Opc 14597, Aripiprex, Abilify MyCite or OPC 31) is a
Chemistry
Salts []
Aripiprazole is typically found in the form of its monohydrate salt.
Stereochemistry []
Aripiprazole is a achiral mixture.
Pharmacology
ATC Classification
In the nervous system (N) aripiprazole acts as a antipsychotic (N05A), aripiprazole (N05AX12), other antipsychotic (N05AX) and psycholeptic (N05).[1]Metabolism
Subjective effects []
| 0xea / Aripiprazole [] | |
|---|---|
Routes:
| |
Experience reports []
There are currently 25+ experience reports involving aripiprazole on Erowid:
- "The Sick Combo" by Meat
- "Diminished Effects" by Herbivore
- "A Strange Time Indeed" by Melly
- "Worthless" by Cheddar
- "I Feel Literally Nothing When I Smoke" by psycholizard
- "The Second Atypical" by cosmicslide
- "Used for Delusional Episode" by Ethan J.
- "Latuda and Other Drugs" by Mj
- "All I Wanted to Do Was Sleep" by Mj
- "The Possibility of a Decrease in Effect" by Feather E.
- "Extreme Restlessness" by Yoshi
- "From One Schizophrenic to Another" by Shadowboxer7777
- "Interfering With Other Drugs" by Bigredox
- "Like a Sugar High" by Raquel
- "The Social Contract" by Rick
- "Methamphetamine and Anti-Psychotics" by Voo
- "Poor Luck with Newer Atypical Antipsychotic" by far2farside8
- "The Anti Psychotic for Autism" by doctorfur
- "Disgusting With Potential?" by SayMe
- "Losing My Ability to Calm Down" by Pretentions
- "The Maw - Daily Bipolar Cocktail and Wean" by Wasted Dreams
- "Excrutiating Discomfort" by 4kg dumbbell
- "Oculogyric Crisis" by Walter Od
- "Being a Narcoleptic" by yellowtail
- "Emotions Tied Up in Goo" by Injun
Legal status []
- Australia: Aripiprazole is a S4 substance.[3]
- Brazil: Aripiprazole is a C1 substance.
- Canada: Aripiprazole is a prescription only substance.
- New Zealand: Aripiprazole is a Prescription only substance.
- United Kingdom: Aripiprazole is a prescription only substance.
- United States: Aripiprazole is a prescription only substance.
- European Union: Aripiprazole is a prescription only substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 60795, Aripiprazole. Accessed May 6, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/60795
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Aripiprazole. UNII: 82VFR53I78. Global Substance Registration System. Accessed May 6, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/82VFR53I78
ARIPENA (Sun Pharma ANZ Pty Ltd). Therapeutic Goods Administration, Government of Australia. . Accessed May 6, 2026. https://www.tga.gov.au/resources/prescription-medicines-registrations/aripena-sun-pharma-anz-pty-ltd