Trimipramine
| Trimipramine | |
|---|---|
 | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 294.4 g/mol [1] |
| Melting point | 45 °C [1] |
| Solubility | Slightly soluble [1] |
| Predicted LogP | 5.8 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C20H26N2 [1] |
| IUPAC name | 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine [1] |
| SMILES | CC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C [1] |
| InChI | InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3 [1] |
| InChIKey | ZSCDBOWYZJWBIY-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 23 – 24 hours |
Trimipramine (also known as Trimipramine, 739-71-9, Trimeprimine, Trimeproprimine, Sapilent, β-Methylimipramine, Trimeprimina, Trimipramina, Trimipraminum or 7162 RP) is a
Chemistry
Stereochemistry []
Trimipramine is a racemic mixture of the enantiomers.
| Stereoisomerism |
|---|
| Stereoisomer enumberation with rdkit |
Pharmacology
ATC Classification
In the nervous system (N) trimipramine acts as a antidepressant (N06A), non (N06AA), psychoanaleptic (N06) and trimipramine (N06AA06).[1]Metabolism
Subjective effects []
| emily / Trimipramine [] | |
|---|---|
Routes:
| |
Legal status []
- Australia: Trimipramine is a S4 substance.
- Brazil: Trimipramine is a C1 substance.[3]
- Canada: Trimipramine is a prescription only substance.
- United Kingdom: Trimipramine is a prescription only substance.
- United States: Trimipramine is a prescription only substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 5584, Trimipramine. Accessed April 24, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/5584
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Trimipramine. UNII: QJ9MUH57H8. Global Substance Registration System. Accessed April 24, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/QJ9MUH57H8
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed April 24, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992