Thiopropamine

Molecular structure via molpic based on CDK

Conformer []

Conformer structure via JSmol

Physical properties []
Molecular mass	141.24 g/mol ^[1]
Predicted LogP	1.8 ^[1]

Structural Identifiers []
Molecular formula	C₇H₁₁NS ^[1]
IUPAC name	1-thiophen-2-ylpropan-2-amine ^[1]
SMILES	CC(CC1=CC=CS1)N ^[1]
InChI	InChI=1S/C7H11NS/c1-6(8)5-7-3-2-4-9-7/h2-4,6H,5,8H2,1H3 ^[1]
InChIKey	NYVQQTOGYLBBDQ-UHFFFAOYSA-N ^[1]

Thiopropamine

Thiopropamine (also known as 2-(2-Aminopropyl)thiophene, 2-Thiopheneethanamine, α-methyl-, 1-(2-Thienyl)-2-propanamine, 1-(Thien-2-yl)propan-2-amine, 1-Methyl-2-(thien-2-yl)ethylamine, (1-Methyl-2-(thiophen-2-yl)ethyl)amine, α-Methyl-2-thiopheneethanamine, α-Methyl-2-thiopheneethylamine, 1-(3,3-diphenylpropyl)amino-3-phenylthiopropane or 1-(thiophen-2-yl)propan-2-amine) is a stimulant substance of the thiopropamine class.

Chemistry

Stereochemistry []

Thiopropamine is a racemic mixture of the optical stereoisomers

Subjective effects []

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Canada: Thiopropamine is a
Germany: Thiopropamine is a Anlage I substance.

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 6484133, Thiopropamine. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/6484133
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Thiopropamine. UNII: N60H4ZDD14. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/N60H4ZDD14

Anodyne