Synephrine

Synephrine

Salts []
Synephrine hemisulfate

Synephrine hydrochloride

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	167.20 g/mol ^[1]
Predicted LogP	-0.6 ^[1]

Structural Identifiers []
Molecular formula	C₉H₁₃NO₂ ^[1]
IUPAC name	4-[1-hydroxy-2-(methylamino)ethyl]phenol ^[1]
SMILES	CNCC(C1=CC=C(C=C1)O)O ^[1]
InChI	InChI=1S/C9H13NO2/c1-10-6-9(12)7-2-4-8(11)5-3-7/h2-5,9-12H,6H2,1H3 ^[1]
InChIKey	YRCWQPVGYLYSOX-UHFFFAOYSA-N ^[1]

Synephrine (also known as Synephrine, Oxedrine, 94-07-5, p-Synephrine, Parasympatol, Analeptin, Sympatol, Simpalon, Synthenate or Sympathol) is a sympathomimetic substance of the phenylethanolamine class.

Chemistry

Salts []

Synephrine is typically found in the form of its hemisulfate and hydrochloride salts.

Stereochemistry []

Synephrine is a racemic mixture of the enantiomers.

Pharmacology

ATC Classification

In the cardiovascular system (C) synephrine acts In the sensory organs (S) synephrine acts

Metabolism

Subjective effects []

Physical effects
Abnormal heartbeat Dehydration Dry mouth Increased blood pressure Increased heart rate Restless legs Shakiness Stamina enhancement Vasoconstriction

Cognitive effects
Thought acceleration Wakefulness

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 7172, Synephrine. Accessed February 17, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/7172
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Synephrine. UNII: PEG5DP7434. Global Substance Registration System. Accessed February 17, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/PEG5DP7434

Anodyne