Rasagiline
| Rasagiline | |
|---|---|
 |
| Salts [] | |
|---|---|
| Rasagiline hydrochloride | |
| Rasagiline mesylate | |
| Rasagiline hemitartrate | |
| Rasagiline besylate | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 171.24 g/mol [1] |
| Solubility | 2.49e-02 g/L [1] |
| Predicted LogP | 1.8 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C12H13N [1] |
| IUPAC name | (1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine [1] |
| SMILES | C#CCN[C@@H]1CCC2=CC=CC=C12 [1] |
| InChI | InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1 [1] |
| InChIKey | RUOKEQAAGRXIBM-GFCCVEGCSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 3 hours |
Rasagiline (also known as N-2-Propynyl-1-indanamine, TV-1030, Rasagilina, NSC-759639, (1R)-N-propargylindan-1-amine, Indan-1-yl-prop-2-ynyl-amine, 1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-,, Dtxsid3041112, Chebi:63620 or Agn-1135) is a monoamine oxidase inhibitor and prodrug substance of the 1-aminoindane class.
Chemistry
Salts []
Rasagiline is typically found in the form of its hydrochloride, mesylate, hemitartrate and besylate salts.
Stereochemistry []
Rasagiline is a absolute mixture.
Pharmacology
ATC Classification
In the nervous system (N) rasagiline acts as a anti (N04), dopaminergic agent (N04B), monoamine oxidase b inhibitor (N04BD) and rasagiline (N04BD02).[1]Metabolism
Rasagiline acts as a prodrug for:
| Metabolic pathways [] |
|---|
|
|
-1-aminoindane.svg)
Interactions
| CYP1A2 | induction / inhibition |
|---|
Subjective effects []
Legal status []
- Australia: Rasagiline is a S4 substance.[3]
- Brazil: Rasagiline is a C1 substance.
- Canada: Rasagiline is a prescription only substance.
- United Kingdom: Rasagiline is a prescription only substance.
- United States: Rasagiline is a prescription only substance.
- European Union: Rasagiline is a prescription only substance.
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3052776, rasagiline. Accessed May 6, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/3052776
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Rasagiline. UNII: 003N66TS6T. Global Substance Registration System. Accessed May 6, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/003N66TS6T
RASAGILINE JAMP/ RASAGILINE GXMED (AA-Med Pty Ltd) {-{!}.