Protonitazepyne

Protonitazepyne

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	408.5 g/mol ^[1]
Predicted LogP	4.5 ^[1]

Structural Identifiers []
Molecular formula	C₂₃H₂₈N₄O₃ ^[1]
IUPAC name	5-nitro-2-[(4-propoxyphenyl)methyl]-1-(2-pyrrolidin-1-ylethyl)benzimidazole ^[1]
SMILES	CCCOC1=CC=C(C=C1)CC2=NC3=C(N2CCN4CCCC4)C=CC(=C3)[N+](=O)[O-] ^[1]
InChI	InChI=1S/C23H28N4O3/c1-2-15-30-20-8-5-18(6-9-20)16-23-24-21-17-19(27(28)29)7-10-22(21)26(23)14-13-25-11-3-4-12-25/h5-10,17H,2-4,11-16H2,1H3 ^[1]
InChIKey	KCRWXNIIXGBPID-UHFFFAOYSA-N ^[1]

Protonitazepyne (also known as N-Pyrrolidino Protonitazene, Protonitazepyne, Dtxsid201356258, 5-nitro-2-(4-propoxybenzyl)-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzimidazole, 1H-Benzimidazole, 5-nitro-2-[(4-propoxyphenyl)methyl]-1-[2-(1-pyrrolidinyl)ethyl]- or 5-Nitro-2-[(4-propoxyphenyl)methyl]-1-(2-pyrrolidin-1-ylethyl)benzimidazole) is a opioid substance of the benzimidazole class.

Chemistry

Stereochemistry []

Protonitazepyne is a achiral mixture.

Subjective effects []

Physical effects
Constipation Cough suppression Difficulty urinating Itchiness Nausea Pain relief Pupil constriction Respiratory depression Sedation Stomach cramp

Cognitive effects
Anxiety suppression Cognitive euphoria Compulsive redosing Increased music appreciation Thought deceleration

Visual effects
Double vision

bonzi / Protonitazepyne []

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 168322728, N-Pyrrolidino Protonitazene. Accessed April 16, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/168322728
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Protonitazepyne. UNII: T3LB6K85C7. Global Substance Registration System. Accessed April 16, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/T3LB6K85C7

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