Pipradrol

Pipradrol

Molecular structure via molpic based on CDK

Physical properties []
Molecular mass	267.4 g/mol ^[1]
Appearance	Crystals from hexane ^[1]
Melting point	97.5 °C ^[1]
Decomposition	When heated to decomposition it emits toxic fumes of /nitrogen oxides/. ^[1]
Predicted LogP	3 ^[1]

Structural Identifiers []
Molecular formula	C₁₈H₂₁NO ^[1]
IUPAC name	diphenyl(piperidin-2-yl)methanol ^[1]
SMILES	C1CCNC(C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)O ^[1]
InChI	InChI=1S/C18H21NO/c20-18(15-9-3-1-4-10-15,16-11-5-2-6-12-16)17-13-7-8-14-19-17/h1-6,9-12,17,19-20H,7-8,13-14H2 ^[1]
InChIKey	XSWHNYGMWWVAIE-UHFFFAOYSA-N ^[1]

Pipradrol (also known as Pipralon, Piridrol, Pyridrol, Pyridrole, Pipradol, α-Pipradol, Gerodyl, Pipradrolum, Pipradrolo or α-(2-Piperidyl)benzhydrol) is a stimulant substance of the 2-benzylpiperidine class.

Chemistry

Stereochemistry []

Pipradrol is a racemic mixture of the enantiomers.

Stereoisomerism
(R)-Pipradrol (S)-Pipradrol
Stereoisomer enumberation with rdkit

Pharmacology

ATC Classification

In the nervous system (N) pipradrol acts as a stimulant (N06B), other psychostimulants and nootropic (N06BX), pipradrol (N06BX15) and psychoanaleptic (N06).^[1]

Subjective effects []

class / Stimulant

Physical effects
Abnormal heartbeat Appetite suppression Dehydration Dry mouth Increased blood pressure Increased heart rate Increased libido Restless legs Shakiness Stamina enhancement Stimulation Teeth grinding Vasoconstriction

Cognitive effects
Analysis enhancement Cognitive euphoria Compulsive redosing Disinhibition Ego inflation Focus enhancement Increased music appreciation Mania Motivation enhancement Suggestibility suppression Thought acceleration Wakefulness

Legal status []

Australia: Pipradrol is a S4 substance.
Brazil: Pipradrol is a B1 substance.^[3]
Canada: Pipradrol is a Schedule IV substance.
Germany: Pipradrol is a Anlage III substance.
New Zealand: Pipradrol is a Class C substance.
United Kingdom: Pipradrol is a Class C substance.
United States: Pipradrol is a Schedule I under the "Controlled Substances Act (CSA)".
United Nations: Pipradrol is a Schedule IV substance.

External links []

References []

National Center for Biotechnology Information. PubChem Compound Summary for CID 10083, Pipradrol. Accessed May 8, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/10083
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Pipradrol. UNII: S6I030E0DA. Global Substance Registration System. Accessed May 8, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/S6I030E0DA
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed May 8, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992

AnodyneWiki