Anodyne| Piperidine | |
|---|---|
| Salts [] | |
|---|---|
| Piperidine hydrochloride | |
| Piperidine phosphate | |
| Molecular structure via molpic based on CDK |
| Rotamer [] | |
|---|---|
| Conformer structure via 3Dmol.js |
| Physical properties [] | |
|---|---|
| Molecular mass | 85.15 g/mol [1] |
| Density | 0.8622 at 68 °F (EPA, 1998) - Less dense than water; will float g/cm3 [1] |
| Appearance | CLEAR, COLORLESS LIQUID [1] |
| Odor | AMINE-LIKE ODOR [1] |
| Taste | BURNING PEPPERY TASTE [1] |
| Melting point | 16 to 19 °F (EPA, 1998) [1] |
| Boiling point | 223 ° [1] |
| Decomposition | ... When heated to decomposition, it emits highly toxic fumes of oxides of /nitrogen oxides/. ... . [1] |
| Solubility | Miscible (NTP, 1992) [1] |
| Predicted LogP | 0.8 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C5H11N [1] |
| IUPAC name | piperidine [1] |
| SMILES | C1CCNCC1 [1] |
| InChI | InChI=1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2 [1] |
| InChIKey | NQRYJNQNLNOLGT-UHFFFAOYSA-N [1] |
| Toxicity [] | |
|---|---|
| LDLo | Rabbit: - subcutaneous: 300 mg/kg - intravenous: 160 mg/kg |
| LD50 | Rat: - oral: 400 mg/kg Mouse: - oral: 30 mg/kg - intraperitoneal: 50 mg/kg Rabbit: - oral: 145 mg/kg - skin: 276 mg/kg Mammal (species unspecified): - oral: 22400 μg/kg |
| LC50 | Mouse: - inhalation: 6000 mg/m3/2H Mammal (species unspecified): - inhalation: 6500 mg/m3 |
Piperidine
Piperidine (also known as Hexahydropyridine, Cyclopentimine, Azacyclohexane, Piperidin, Cypentil, Hexazane, Pentamethyleneimine, Pentamethylenimine, Perhydropyridine or Pyridine, hexahydro-) is a
Chemistry
Salts []
Piperidine is typically found in the form of its hydrochloride and phosphate salts.
Stereochemistry []
Piperidine is a achiral mixture
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 8082, Piperidine. Accessed September 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/8082
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Piperidine. UNII: 67I85E138Y. Global Substance Registration System. Accessed September 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/67I85E138Y