| Phendimetrazine | |
|---|---|
| Salts [] | |
|---|---|
| %!s( | |
| %!s( | |
| %!s( | |
| %!s( | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 191.27 g/mol [1] |
| Appearance | White powder [1] |
| Odor | Odorless [1] |
| Taste | Bitter [1] |
| Melting point | 208 °C [1] |
| Boiling point | 122-124 °C at 8 mm Hg; 134-135 °C at 12 mm Hg [1] |
| Decomposition | When heated to decomp it emits very toxic fumes of /nitrogen oxides and hydrogen chloride/. /Phendimetrazine hydrochloride/ [1] |
| Solubility | Free sol in water; very slightly sol in alcohol; practically insol in chloroform and ether. [1] |
| Predicted LogP | 1.9 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C12H17NO [1] |
| IUPAC name | (2S,3S)-3,4-dimethyl-2-phenylmorpholine [1] |
| SMILES | C[C@H]1[C@@H](OCCN1C)C2=CC=CC=C2 [1] |
| InChI | InChI=1S/C12H17NO/c1-10-12(14-9-8-13(10)2)11-6-4-3-5-7-11/h3-7,10,12H,8-9H2,1-2H3/t10-,12+/m0/s1 [1] |
| InChIKey | MFOCDFTXLCYLKU-CMPLNLGQSA-N [1] |
Phendimetrazine
Phendimetrazine (also known as Mephenmetrazine, Fendimetrazina, Phendimetrazinum, Sedafamen, (2S,3S)-3,4-Dimethyl-2-phenylmorpholine, 3,4-Dimethyl-2-phenyltetrahydro-1,4-oxazine, Morpholine, 3,4-dimethyl-2-phenyl-, (2S-trans)-, Morpholine, 3,4-dimethyl-2-phenyl-, (+)-, (2S,3S)-3,4-dimethyl-2-phenyl-morpholine or 211-204-6) is a
Chemistry
Salts []
Phendimetrazine is typically found in the form of its fumarate, hydrochloride, succinate and tartrate salts.
Stereochemistry []
Phendimetrazine is a absolute mixture
Pharmacology
Phendimetrazine acts as a prodrug for:
| Active metabolites [] |
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See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 30487, Phendimetrazine. Accessed July 19, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/30487
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Phendimetrazine. UNII: AB2794W8KV. Global Substance Registration System. Accessed July 19, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/AB2794W8KV
Anodyne