Anodyne

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Pentobarbital
Generated by the Chemistry Development Kit (http://github.com/cdk)
Salts
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Sodium
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
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Physical properties
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226.27 g/mol [1]
AppearanceCrystals from alcohol [1]
OdorPractically odorless [1]
Melting point130 °C [1]
DecompositionWhen heated to decomposition it emits toxic fumes of /nitric oxide/. [1]
SolubilityA white, hygroscopic, crystalline powder or granules, odorless or with a slight characteristic odor, with a slightly bitter taste. Very sol in water and alcohol; practically insol in ether. A 10% soln in water has pH of 9.6 to 11 and slowly decomposes. /Pentobarbitone sodium/ [1]
2.1 [1]
Structural Identifiers
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C11H18N2O3 [1]
5-ethyl-5-pentan-2-yl-1,3-diazinane-2,4,6-trione [1]
CCCC(C)C1(C(=O)NC(=O)NC1=O)CC [1]
InChI=1S/C11H18N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16) [1]
InChIKeyWEXRUCMBJFQVBZ-UHFFFAOYSA-N [1]
Dosing
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Elimination half-life15 – 48 hours

Pentobarbital

Pentobarbital (also known as Pentobarbital, pentobarbital, Pentobarbitone, Mebubarbital, Ethaminal, Mebumal, Pentobarbituric acid, Dorsital, Rivadorm or Pentobarbiturate) is a substance of the barbiturate class.

Chemistry

Salts []

Pentobarbital is typically found in the form of its sodium salt.

 []

Pentobarbital is a racemic mixture of the optical stereoisomers

Stereoisomers
(+)-PentobarbitalGenerated by the Chemistry Development Kit (http://github.com/cdk)
(R)-PentobarbitalGenerated by the Chemistry Development Kit (http://github.com/cdk)

Experience reports []

There are currently 3 experience reports involving pentobarbital on OpenErowid:

Legal status []

  • Australia: Pentobarbital is a S8 substance.[3]
  • Brazil: Pentobarbital is a B1 substance.
  • Canada: Pentobarbital is a Schedule IV substance.
  • Germany: Pentobarbital is a Anlage III substance.
  • United Kingdom: Pentobarbital is a Class B substance.
  • United States: Pentobarbital is a Schedule I under the "Controlled Substances Act (CSA)".
  • United Nations: Pentobarbital is a Schedule III substance.

See also []

  • Substituted barbiturates
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 4737, Pentobarbital. Accessed July 13, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/4737

    2. U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Pentobarbital. UNII: I4744080IR. Global Substance Registration System. Accessed July 13, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/I4744080IR

    3. Therapeutic Goods (Poisons Standard—June 2024) Instrument 2024. May 30, 2024. Accessed July 13, 2025. https://www.legislation.gov.au/F2024L00589/latest/text