Anodyne| vitamin B3 | |
|---|---|
| Salts [] | |
|---|---|
| Sodium Niacin | |
| Niacin hydrochloride | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 123.11 g/mol [1] |
| Density | 1.473 (NTP, 1992) - Denser than water; will sink g/cm3 [1] |
| Appearance | Needles from alcohol or water [1] |
| Odor | Odorless [1] |
| Taste | Sour taste [1] |
| Melting point | 457 ° [1] |
| Boiling point | Sublimes (NTP, 1992) [1] |
| Decomposition | Hazardous decomposition products formed under fire conditions - Carbon oxides, nitrogen oxides (NOx). [1] |
| Solubility | >18.5 [ug/mL] (The mean of the results at pH 7.4) [1] |
| Predicted LogP | 0.4 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C6H5NO2 [1] |
| IUPAC name | pyridine-3-carboxylic acid [1] |
| SMILES | C1=CC(=CN=C1)C(=O)O [1] |
| InChI | InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9) [1] |
| InChIKey | PVNIIMVLHYAWGP-UHFFFAOYSA-N [1] |
| Toxicity [] | |
|---|---|
| TDLo | Human - male: - oral: 31200 mg/kg/78 - oral: 9713 mg/kg/58W - intravenous: 357 μg/kg - oral: 2571 mg/kg/90D |
| LDLo | Rat: - intravenous: 3500 mg/kg Guinea pig: - intravenous: 3500 mg/kg |
| LD50 | Rat: - oral: 7 gm/kg - intraperitoneal: 730 mg/kg - subcutaneous: 5 gm/kg Mouse: - oral: 3720 mg/kg - intraperitoneal: 358 mg/kg - subcutaneous: 3500 mg/kg - intravenous: 5 gm/kg Rabbit: - oral: 4550 mg/kg |
Niacin
Niacin (also known as nicotinic acid, Pyridine-3-carboxylic acid, 3-pyridinecarboxylic acid, 3-Carboxypyridine, vitamin B3, wampocap, Niaspan, Acidum nicotinicum, Apelagrin or Pellagrin) is a vitamin substance of the carboxylic acid class.
Chemistry
Salts []
Niacin is typically found in the form of its sodium and hydrochloride salts.
Stereochemistry []
Niacin is a achiral mixture
Legal status
- United States: Niacin is a OTC substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 938, Niacin. Accessed September 14, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/938
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Niacin. UNII: 2679MF687A. Global Substance Registration System. Accessed September 14, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/2679MF687A