Anodyne| Loprazolam | |
|---|---|
 | |
| Molecular structure via molpic based on CDK |
| Conformer [] | |
|---|---|
| Conformer structure via JSmol | |
| Physical properties [] | |
|---|---|
| Molecular mass | 464.9 g/mol [1] |
| Predicted LogP | 2.9 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C23H21ClN6O3 [1] |
| IUPAC name | (2Z)-6-(2-chlorophenyl)-2-[(4-methylpiperazin-1-yl)methylidene]-8-nitro-4H-imidazo[1,2-a][1,4]benzodiazepin-1-one [1] |
| SMILES | CN1CCN(CC1)/C=C\2/C(=O)N3C(=N2)CN=C(C4=C3C=CC(=C4)[N+](=O)[O-])C5=CC=CC=C5Cl [1] |
| InChI | InChI=1S/C23H21ClN6O3/c1-27-8-10-28(11-9-27)14-19-23(31)29-20-7-6-15(30(32)33)12-17(20)22(25-13-21(29)26-19)16-4-2-3-5-18(16)24/h2-7,12,14H,8-11,13H2,1H3/b19-14- [1] |
| InChIKey | UTEFBSAVJNEPTR-RGEXLXHISA-N [1] |
| Dosing [] | |
|---|---|
| Elimination half-life | 6 – 12 hours |
Loprazolam
Loprazolam (also known as Triazulenone, Loprazolamum, triazulenone, (Z)-isomer, Triazulenone, (z)-, Dormonoct, Ru-31158 free base, (Z)-6-(o-Chlorophenyl)-2,4-dihydro-2-((4-methyl-1-piperazinyl)methylene)-8-nitro-1H-imidazo(1,2-a)(1,4)benzodiazepin-1-one, HR 158, 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-6-(2-chlorophenyl)-2-((4-methyl-1-piperazinyl)methylene)-8-nitro- or (2Z)-6-(2-chlorophenyl)-2,4-dihydro-2-((4-methyl-1-piperazinyl)methylene)-8-nitro-1h-imidazo(1,2-a)(1,4)benzodiazepin-1-one) is a
Chemistry
Stereochemistry []
Loprazolam is a achiral mixture
Legal status
- Brazil: Loprazolam is a B1 substance.[3]
- Canada: Loprazolam is a Schedule IV substance.
- Germany: Loprazolam is a prescription only/Anlage III substance.
- United States: Loprazolam is a Schedule I under the "Controlled Substances Act (CSA)".
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3033860, Loprazolam. Accessed July 4, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/3033860
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Loprazolam. UNII: 759N8462G8. Global Substance Registration System. Accessed July 4, 2025. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/759N8462G8
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed July 4, 2025. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992