Lamotrigine
| BW-430C, BW430C | |
|---|---|
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 256.09 g/mol [1] |
| Appearance | White to pale cream-colored powder. Crystals from isopropanol [1] |
| Melting point | 177-181 [1] |
| Boiling point | 503.1±60.0 [1] |
| Solubility | In water, 170 mg/L at 25 °C [1] |
| Predicted LogP | 1.4 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C9H7Cl2N5 [1] |
| IUPAC name | 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine [1] |
| SMILES | C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N [1] |
| InChI | InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16) [1] |
| InChIKey | PYZRQGJRPPTADH-UHFFFAOYSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 29 hours |
| Dosing[] |
|---|
| Oral [] | |
|---|---|
| Light | ≤ 27.2 mg(10x - 66.7%) |
| Common | 27.2 mg |
| Strong | 25 - 50 mg(5x - 33.3%) |
| Heavy | 50 mg |
| Extreme | 50 mg + |
Statistically derived dosages via DBI-IGS We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly. |
Lamotrigine (also known as 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine, Lamictal, Lamictal Cd, Lamotrigina, Lamictal XR, Lamotriginum, BW 430C, 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine, BW-430C or Lamictal ODT) is a
Chemistry
Stereochemistry []
Lamotrigine is a achiral mixture.
Druglikeness
Lipinski's rule of five
Lamotrigine matches Lipinski's rule of five.Pharmacology
ATC Classification
In the nervous system (N) lamotrigine acts as a antiepileptic (N03), antiepileptic (N03A), lamotrigine (N03AX09) and other antiepileptic (N03AX).[1]Subjective effects []
| emily / Lamotrigine [] | |
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| Pilz / Lamotrigine [] | |
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Legal status []
- Australia: Lamotrigine is a S4 substance.
- Brazil: Lamotrigine is a C1 substance.[2]
- Canada: Lamotrigine is a prescription only substance.
- United Kingdom: Lamotrigine is a prescription only substance.
- United States: Lamotrigine is a prescription only substance.
- European Union: Lamotrigine is a prescription only substance.
See also []
External links []
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 3878, Lamotrigine. Accessed June 24, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/3878
Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial. Diário Oficial da União. March 31, 2023. Accessed June 24, 2026. https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992