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Baclofen
Generated by the Chemistry Development Kit (http://github.com/cdk)
Molecular structure via molpic based on CDK
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Physical properties
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213.66 g/mol [1]
Melting point372 to 376 °F (NTP, 1992) [1]
Solubilityless than 1 mg/mL at 64 °F (NTP, 1992) [1]
-1 [1]
Structural Identifiers
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C10H12ClNO2 [1]
4-amino-3-(4-chlorophenyl)butanoic acid [1]
C1=CC(=CC=C1C(CC(=O)O)CN)Cl [1]
InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14) [1]
InChIKeyKPYSYYIEGFHWSV-UHFFFAOYSA-N [1]

Baclofen

Baclofen (also known as Baclofen, baclofen, Lioresal, 4-Amino-3-(4-chlorophenyl)butanoic acid, Baclon, Kemstro, Baclofene, Baclofeno, Baclofenum or Baclophen) is a substance of the gabapentinoid class.

Chemistry

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Baclofen is a racemic mixture of the

Stereoisomers
(S)-BaclofenGenerated by the Chemistry Development Kit (http://github.com/cdk)
(R)-BaclofenGenerated by the Chemistry Development Kit (http://github.com/cdk)

Experience reports []

There are currently 14 experience reports involving baclofen on OpenErowid:

See also []

  • Substituted gabapentinoids
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 2284, Baclofen. Accessed August 6, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/2284