Sibutramine

Salts []
Sibutramine hydrochloride
Sibutramine mesylate
Sibutramine maleate

Molecular structure via molpic
Conformer structure via 3Dmol.js
Molecular formula	C17H26ClN[1]
Molecular mass	279.8 g/mol[1]
Predicted LogP	5.4[1]
Melting point	191-192 °C[1]
Decomposition	When heated to decomposition, material emits very toxic fumes of /hydrogen chloride/ and /nitrogen oxides/. Emits toxic fumes[1]
Solubility	9.40e-04 g/L[1]
Chirality	racemic[2]

Identifiers []
IUPAC name	1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine[1]
SMILES	CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C[1]
InChI	InChI=1S/C17H26ClN/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14/h6-9,13,16H,5,10-12H2,1-4H3[1]
InChIKey	UNAANXDKBXWMLN-UHFFFAOYSA-N[1]

Dosing
Elimination half-life	1 hour (sibutramine), 14 hours (M1) & 16 hours (M2)

Sibutramine

(Redirected from (+)-Sibutramine)

Sibutramine (also known as Medaria, Butramin, Sibutramina, (+/-)-Sibutramine, racemic sibutramine, Cf-alli, Sibutraminum, Smr000238156, S-Sibutramine or BTS 54 524) is a stimulant substance of the amphetamine class.

Chemistry

Sibutramine is typically found in the form of its hydrochloride, mesylate and maleate salts.

Stereochemistry

(RS)-Sibutramine is a racemic mixture of the optical stereoisomers:

Stereoisomers []
(+)-Sibutramine (-)-Sibutramine

Legal status

• Brazil: Sibutramine is a B2 substance.
• United States: Sibutramine is a Schedule IV substance.

See also

• Depressant
• Antidepressant
• Amphetamine
• Substituted amphetamines
• Anodyne

External links

• Sibutramine (Wikipedia)
• Sibutramine / (+)-Sibutramine / (-)-Sibutramine (Wikidata)
• Sibutramine (DrugBank)
• Sibutramine / (+)-Sibutramine / (-)-Sibutramine (PubChem)
• Sibutramine / (-)-Sibutramine (ChEMBL)
• Sibutramine (ChEBI)
• Sibutramine / (+)-Sibutramine / (-)-Sibutramine (Common Chemistry)
• Sibutramine (HMDB)
• Sibutramine (KEGG)
• Sibutramine / (+)-Sibutramine / (-)-Sibutramine (UNII)
• Sibutramine / (+)-Sibutramine / (-)-Sibutramine (EPA DSSTox)